PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30014643-0 2018 [The Relationship of Clinicopathology of p16 in Non-small Cell Lung Cancer and 5-nitrogen impurity-2"-deoxycytidine-nitrogen Impurity on the Influence of p16 Expression in Lung Cancer A549 Cells]. Deoxycytidine 99-115 cyclin dependent kinase inhibitor 2A Homo sapiens 154-157 11098088-3 2000 In the present experiments, we have studied the effects of the demethylating agent, 5-aza-2"-deoxycytidine (5-AZA/decitabine), on the expression of aberrant p16INK4A RNA transcripts and the CDK-retinoblastoma gene pathway in HCC cell lines with p16INK4A promoter hypermethylation. Deoxycytidine 93-106 cyclin dependent kinase inhibitor 2A Homo sapiens 157-165 11098088-3 2000 In the present experiments, we have studied the effects of the demethylating agent, 5-aza-2"-deoxycytidine (5-AZA/decitabine), on the expression of aberrant p16INK4A RNA transcripts and the CDK-retinoblastoma gene pathway in HCC cell lines with p16INK4A promoter hypermethylation. Deoxycytidine 93-106 cyclin dependent kinase inhibitor 2A Homo sapiens 245-253 30014643-1 2018 OBJECTIVE: To investigate the relationship between expression of tumor suppressor gene p16 in non-small cell lung cancer (NSCLC) tissues and clinicopathological parameters,to further study on DNA methyltransferase inhibitors 5-nitrogen impurity-2"-deoxycytidine (5-Aza-CdR) in human lung cancer cell line A549 in regulating the expression of p16. Deoxycytidine 245-261 cyclin dependent kinase inhibitor 2A Homo sapiens 87-90 22738793-8 2012 In addition, stable transfection of the p16ATF induced demethylation of p16 CpG island and trimethylation of histone H3K4, and inhibited recruitment of DNA methyltransferase 1 and trimethylation of H3K9 and H3K27 in the p16 promoter in H1299 cells without 5"-aza-deoxycytidine pretreatment. Deoxycytidine 263-276 cyclin dependent kinase inhibitor 2A Homo sapiens 40-43