PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29535328-0 2018 Use of quercetin in animal feed: effects on the P-gp expression and pharmacokinetics of orally administrated enrofloxacin in chicken. Quercetin 7-16 phosphoglycolate phosphatase Gallus gallus 48-52 29535328-2 2018 Quercetin has a potential to modulate P-gp in rodents, however, its effects on P-gp modulation in chicken are still unclear. Quercetin 0-9 phosphoglycolate phosphatase Gallus gallus 38-42 29535328-2 2018 Quercetin has a potential to modulate P-gp in rodents, however, its effects on P-gp modulation in chicken are still unclear. Quercetin 0-9 phosphoglycolate phosphatase Gallus gallus 79-83 29535328-3 2018 Herein, study reports role of quercetin in modulation of P-gp expression and subsequent effects on the pharmacokinetics of enrofloxacin in broilers. Quercetin 30-39 phosphoglycolate phosphatase Gallus gallus 57-61 29535328-5 2018 Absorption rate constant and apparent permeability coefficient of rhodamine 123 were decreased, reflecting efflux function of P-gp in chicken intestine increased by quercetin. Quercetin 165-174 phosphoglycolate phosphatase Gallus gallus 126-130 29535328-8 2018 Results provide convincing evidence that quercetin induced P-gp expression in tissues by possible interaction with CXR, and consequently reducing bioavailability of orally administered enrofloxacin through restricting its intestinal absorption and liver/kidney clearance in broilers. Quercetin 41-50 phosphoglycolate phosphatase Gallus gallus 59-63