PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30361436-5 2018 Studies with heterologously expressed human GLUT1, -3, or -4 reveal that quercetin-GLUT1 and -GLUT4 interactions are stronger than quercetin-GLUT3 interactions, that epicatechin gallate (ECG) is more selective for GLUT1, and that epigallocatechin gallate (EGCG) is less GLUT isoform-selective. Quercetin 73-82 solute carrier family 2 member 1 Homo sapiens 44-49 31602954-4 2019 The results showed that both quercetin and glabridin could decrease the glucose uptake capacity of breast cancer cells by down-regulating the protein expression of GLUT1. Quercetin 29-38 solute carrier family 2 member 1 Homo sapiens 164-169 30361436-5 2018 Studies with heterologously expressed human GLUT1, -3, or -4 reveal that quercetin-GLUT1 and -GLUT4 interactions are stronger than quercetin-GLUT3 interactions, that epicatechin gallate (ECG) is more selective for GLUT1, and that epigallocatechin gallate (EGCG) is less GLUT isoform-selective. Quercetin 73-82 solute carrier family 2 member 1 Homo sapiens 83-88 30361436-5 2018 Studies with heterologously expressed human GLUT1, -3, or -4 reveal that quercetin-GLUT1 and -GLUT4 interactions are stronger than quercetin-GLUT3 interactions, that epicatechin gallate (ECG) is more selective for GLUT1, and that epigallocatechin gallate (EGCG) is less GLUT isoform-selective. Quercetin 73-82 solute carrier family 2 member 1 Homo sapiens 83-88 30361436-5 2018 Studies with heterologously expressed human GLUT1, -3, or -4 reveal that quercetin-GLUT1 and -GLUT4 interactions are stronger than quercetin-GLUT3 interactions, that epicatechin gallate (ECG) is more selective for GLUT1, and that epigallocatechin gallate (EGCG) is less GLUT isoform-selective. Quercetin 73-82 solute carrier family 2 member 1 Homo sapiens 44-48 27033602-4 2016 The GLUT specificity of the probes was validated with quercetin, which is both a permeant substrate via GLUTs and a high-affinity inhibitor of GLUT-mediated glucose transport. Quercetin 54-63 solute carrier family 2 member 1 Homo sapiens 4-8 30025823-5 2018 The further experiments exhibited that quercetin successfully blocked cell glycolysis by inhibiting the level of glucose uptake and the production of lactic acid, and also decreased the level of glycolysis-related proteins Pyruvate kinase M2 (PKM2), Glucose transporter1(GLUT1) and Lactate dehydrogenase A (LDHA). Quercetin 39-48 solute carrier family 2 member 1 Homo sapiens 271-276 26706102-5 2016 The results showed that the sugar-conjugated platinum(II) complexes can be recognized by the glucose recognition binding site of GLUT1 and their cell killing effect depends highly on the GLUT1 inhibitor, quercetin. Quercetin 204-213 solute carrier family 2 member 1 Homo sapiens 129-134 26706102-5 2016 The results showed that the sugar-conjugated platinum(II) complexes can be recognized by the glucose recognition binding site of GLUT1 and their cell killing effect depends highly on the GLUT1 inhibitor, quercetin. Quercetin 204-213 solute carrier family 2 member 1 Homo sapiens 187-192 27033602-4 2016 The GLUT specificity of the probes was validated with quercetin, which is both a permeant substrate via GLUTs and a high-affinity inhibitor of GLUT-mediated glucose transport. Quercetin 54-63 solute carrier family 2 member 1 Homo sapiens 104-108 26943884-3 2016 Flavonoids, like quercetin, are GLUT-1 competitive inhibitors and may be considered as potential therapeutic agents for PLTs. Quercetin 17-26 solute carrier family 2 member 1 Homo sapiens 32-38 26943884-9 2016 Incubation with quercetin induced an increase in GLUT-1 membrane expression and a consequent reduction in the cytoplasmic fraction, observed as a decrease in (18)F-FDG uptake, indicating a GLUT-1 competitive inhibition. Quercetin 16-25 solute carrier family 2 member 1 Homo sapiens 49-55 26943884-9 2016 Incubation with quercetin induced an increase in GLUT-1 membrane expression and a consequent reduction in the cytoplasmic fraction, observed as a decrease in (18)F-FDG uptake, indicating a GLUT-1 competitive inhibition. Quercetin 16-25 solute carrier family 2 member 1 Homo sapiens 189-195 26943884-11 2016 Thus, the use of quercetin seems to be a promising approach for PLTs through GLUT-1 competitive inhibition. Quercetin 17-26 solute carrier family 2 member 1 Homo sapiens 77-83 21899256-3 2011 Here we analyzed the interaction of GLUT1 with quercetin (a flavone), genistein (an isoflavone), and tyrphostin A47 and B46 to evaluate if they share one common or have several binding sites on the protein. Quercetin 47-56 solute carrier family 2 member 1 Homo sapiens 36-41 21899256-4 2011 Kinetic assays showed that genistein, quercetin, and tyrphostin B46 behave as competitive inhibitors of equilibrium exchange and zero-trans uptake transport and noncompetitive inhibitors of net sugar exit out of human red cells, suggesting that they interact with the external surface of the GLUT1 molecule. Quercetin 38-47 solute carrier family 2 member 1 Homo sapiens 292-297 34469746-8 2021 This method was successfully applied to quantify the uptake of GLUT1-mediated 2-NBDG, and the results clearly indicated inhibition of GLUT1 by WZB117 and quercetin (two potent glucose transporter inhibitors) in the GLUT1-HEK293T cell model. Quercetin 154-163 solute carrier family 2 member 1 Homo sapiens 63-68 34469746-8 2021 This method was successfully applied to quantify the uptake of GLUT1-mediated 2-NBDG, and the results clearly indicated inhibition of GLUT1 by WZB117 and quercetin (two potent glucose transporter inhibitors) in the GLUT1-HEK293T cell model. Quercetin 154-163 solute carrier family 2 member 1 Homo sapiens 134-139 34469746-8 2021 This method was successfully applied to quantify the uptake of GLUT1-mediated 2-NBDG, and the results clearly indicated inhibition of GLUT1 by WZB117 and quercetin (two potent glucose transporter inhibitors) in the GLUT1-HEK293T cell model. Quercetin 154-163 solute carrier family 2 member 1 Homo sapiens 215-220 16407180-0 2006 Docking studies show that D-glucose and quercetin slide through the transporter GLUT1. Quercetin 40-49 solute carrier family 2 member 1 Homo sapiens 80-85