PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28545280-0	2017	[Impacts of early metoprolol intervention on connexin 43 and phosphorylated connexin 43 expression in rabbits with experimental myocardial infarction].	Metoprolol	18-28	gap junction alpha-1 protein	Oryctolagus cuniculus	45-56	
28545280-0	2017	[Impacts of early metoprolol intervention on connexin 43 and phosphorylated connexin 43 expression in rabbits with experimental myocardial infarction].	Metoprolol	18-28	gap junction alpha-1 protein	Oryctolagus cuniculus	76-87	
28545280-1	2017	Objective: To investigate the early intervention effects of metoprolol on connexin 43(Cx43) and phosphorylated Cx43 (p-Cx43) expression in rabbits with post myocardial infarction.	Metoprolol	60-70	gap junction alpha-1 protein	Oryctolagus cuniculus	74-85	
28545280-1	2017	Objective: To investigate the early intervention effects of metoprolol on connexin 43(Cx43) and phosphorylated Cx43 (p-Cx43) expression in rabbits with post myocardial infarction.	Metoprolol	60-70	gap junction alpha-1 protein	Oryctolagus cuniculus	86-90	
28545280-16	2017	Conclusion: Metoprolol treatment, especially the early metoprolol treatment (within 24 hours after LAD ligation), could significantly improve VFT by ameliorating the distribution and dephosphorylation of myocardial Cx43 in rabbits with experimental myocardial infarction.	Metoprolol	12-22	gap junction alpha-1 protein	Oryctolagus cuniculus	215-219	
28545280-16	2017	Conclusion: Metoprolol treatment, especially the early metoprolol treatment (within 24 hours after LAD ligation), could significantly improve VFT by ameliorating the distribution and dephosphorylation of myocardial Cx43 in rabbits with experimental myocardial infarction.	Metoprolol	55-65	gap junction alpha-1 protein	Oryctolagus cuniculus	215-219	
29434781-0	2018	Metoprolol protects cardiomyocytes in rabbit model of heart failure by regulating Cx43.	Metoprolol	0-10	gap junction alpha-1 protein	Oryctolagus cuniculus	82-86	
29434781-10	2018	Compared with non-infarction group, expression of Cx43 in infarction group was significantly decreased or even disappeared, while the decrease in expression level of Cx43 and the degree of dispersion were lower in metoprolol group than in control group.	Metoprolol	214-224	gap junction alpha-1 protein	Oryctolagus cuniculus	50-54	
29434781-10	2018	Compared with non-infarction group, expression of Cx43 in infarction group was significantly decreased or even disappeared, while the decrease in expression level of Cx43 and the degree of dispersion were lower in metoprolol group than in control group.	Metoprolol	214-224	gap junction alpha-1 protein	Oryctolagus cuniculus	166-170	
29434781-12	2018	In infarction group, expression level of Cx43 protein and mRNA in the metoprolol group were significantly higher than those in control group (P<0.05).	Metoprolol	70-80	gap junction alpha-1 protein	Oryctolagus cuniculus	41-45	
29434781-13	2018	The results showed that metoprolol can protect cardiomyocytes after myocardial infarction, and the possible mechanism is related to the regulation of Cx43 expression in cardiomyocytes.	Metoprolol	24-34	gap junction alpha-1 protein	Oryctolagus cuniculus	150-154