PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12052823-8 2002 Treatment with two pharmacological inhibitors of NF-kappa B, SN50 and N-tosyl-l-phenylalanine chloromethyl ketone (TPCK), blocks TNF-induced Akt activation. Tosylphenylalanyl Chloromethyl Ketone 70-113 tumor necrosis factor Mus musculus 129-132 11526436-8 2001 Both TNF-induced necrosis and necrosis induced by anti-Fas in the presence of the caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone are prevented by the serine protease inhibitor N-tosyl-L-phenylalanine chloromethylketone and the oxygen radical scavenger butylated hydroxyanisole, while Fas-induced apoptosis is not affected. Tosylphenylalanyl Chloromethyl Ketone 201-243 tumor necrosis factor Mus musculus 5-8 9415036-0 1997 Tosylphenylalanine chloromethyl ketone inhibits TNF-alpha mRNA synthesis in the presence of activated NF-kappa B in RAW 264.7 macrophages. Tosylphenylalanyl Chloromethyl Ketone 0-38 tumor necrosis factor Mus musculus 48-57 9415036-1 1997 Serine proteinase inhibitors such as N-tosyl-L-phenylalanine chloromethyl ketone (TPCK) and N alpha-p-tosyl-L-lysine chloromethyl ketone (TLCK) were shown to inhibit production of tumour necrosis factor-alpha (TNF-alpha) in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages. Tosylphenylalanyl Chloromethyl Ketone 37-80 tumor necrosis factor Mus musculus 210-219 9367540-4 1997 N-tosyl-l-phenylalanine chloromethyl ketone and Nalpha-p-tosyl-l-lysine chloromethyl ketone, two serine protease inhibitors, has a protective effect on TNF-induced killing, while Fas-mediated cell death was rather enhanced. Tosylphenylalanyl Chloromethyl Ketone 0-43 tumor necrosis factor Mus musculus 152-155