PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28871089-4	2017	Consequently, CD81 depletion results in SAMHD1 increased expression, decreasing the availability of deoxynucleoside triphosphates (dNTP) and thus HIV-1 reverse transcription.	deoxynucleoside triphosphates	100-129	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	40-46	
30336972-1	2019	SAMHD1 is a host triphosphohydrolase that degrades intracellular deoxynucleoside triphosphates (dNTPs) to a lower level that restricts viral DNA synthesis, and thus prevents replication of diverse viruses in nondividing cells.	deoxynucleoside triphosphates	65-94	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
29249320-1	2018	SAMHD1 restricts lentiviruses by limiting availability of deoxynucleoside triphosphates for reverse transcription.	deoxynucleoside triphosphates	58-87	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
28251415-1	2017	The human sterile alpha motif SAM and HD domain-containing protein 1 (SAMHD1) restricts in non-cycling cells type the infection of a large range of retroviruses including HIV-1, reducing the intracellular pool concentration of deoxynucleoside triphosphates (dNTPs) required for the reverse transcription of the viral genome.	deoxynucleoside triphosphates	227-256	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	70-76	
25926647-2	2015	MDDC are poorly susceptible to HIV-1, in part due to the presence of SAMHD1, a cellular enzyme that depletes intracellular deoxynucleoside triphosphates (dNTPs) and degrades viral RNA.	deoxynucleoside triphosphates	123-152	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	69-75	
28220857-1	2017	SAMHD1 is an intracellular enzyme that specifically degrades deoxynucleoside triphosphates into component nucleoside and inorganic triphosphate.	deoxynucleoside triphosphates	61-90	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
23986575-3	2013	SAMHD1 is thought to work by depleting the pool of intracellular deoxynucleoside triphosphates but has also been reported to have exonuclease activity that could allow it to degrade the viral genomic RNA or viral reverse-transcribed DNA.	deoxynucleoside triphosphates	65-94	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
24161438-2	2013	SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase that degrades the intracellular pool of deoxynucleoside triphosphates available during early reverse transcription.	deoxynucleoside triphosphates	101-130	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
24867973-1	2014	Sterile alpha motif- and histidine/aspartic acid domain-containing protein 1 (SAMHD1) limits HIV-1 replication by hydrolyzing deoxynucleoside triphosphates (dNTPs) necessary for reverse transcription.	deoxynucleoside triphosphates	126-155	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	78-84	
22327569-2	2012	Here we found that SAMHD1 restricted infection by hydrolyzing intracellular deoxynucleoside triphosphates (dNTPs), lowering their concentrations to below those required for the synthesis of the viral DNA by reverse transcriptase (RT).	deoxynucleoside triphosphates	76-105	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	19-25	
23601106-1	2013	SAMHD1 is a cellular enzyme that depletes intracellular deoxynucleoside triphosphates (dNTPs) and inhibits the ability of retroviruses, notably HIV-1, to infect myeloid cells.	deoxynucleoside triphosphates	56-85	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
23872947-3	2013	SAMHD1 is a triphosphohydrolase that depletes the cellular pool of deoxynucleoside triphosphates, thereby preventing reverse transcription of retroviral genomes.	deoxynucleoside triphosphates	67-96	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
23858451-1	2013	Sterile alpha motif and HD-domain containing protein 1 (SAMHD1) is a triphosphohydrolase converting deoxynucleoside triphosphates (dNTPs) to deoxynucleosides.	deoxynucleoside triphosphates	100-129	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	56-62	
23269793-2	2013	SAMHD1 depletes the intracellular pool of deoxynucleoside triphosphates, thus impairing HIV-1 reverse transcription and productive infection in noncycling cells.	deoxynucleoside triphosphates	42-71	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	0-6	
22908011-7	2012	Studies have since revealed that SAMHD1 degrades deoxynucleoside triphosphates (dNTPs), which are components of viral genomic cDNA, in order to deprive viruses of dNTPs.	deoxynucleoside triphosphates	49-78	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	33-39	
22056990-5	2011	Here we show that human SAMHD1 is a potent dGTP-stimulated triphosphohydrolase that converts deoxynucleoside triphosphates to the constituent deoxynucleoside and inorganic triphosphate.	deoxynucleoside triphosphates	93-122	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	24-30	
32850489-1	2020	Sterile alpha motif (SAM) and histidine-aspartate (HD) domain-containing protein 1 (SAMHD1) acts as a restriction factor for several RNA and DNA viruses by limiting the intracellular pool of deoxynucleoside triphosphates.	deoxynucleoside triphosphates	191-220	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	Homo sapiens	84-90