PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11012615-8 2000 The induction of IL-8 mRNA by poly-L-arginine was significantly inhibited by actinomycin D. polyarginine 30-45 C-X-C motif chemokine ligand 8 Homo sapiens 17-21 12438368-3 2002 As CAP37 and protamines share high levels of arginine content, we tested different synthetic poly-L-amino acids and found that poly-L-arginine, and to a lesser extent poly-L-lysine, increased IL-8 production in LPS-stimulated human whole blood. polyarginine 127-142 C-X-C motif chemokine ligand 8 Homo sapiens 192-196 26246181-0 2016 Poly-L-Arginine Acts Synergistically with LPS to Promote the Release of IL-6 and IL-8 via p38/ERK Signaling Pathways in NCI-H292 Cells. polyarginine 0-15 C-X-C motif chemokine ligand 8 Homo sapiens 81-85 26246181-2 2016 The pharmacological function of MBP can be mimicked by poly-L-arginine (PLA), however, the potential signaling mechanisms of LPS-PLA-induced release of the inflammatory cytokines interleukin (IL)-6 and IL-8 remain unclear. polyarginine 55-70 C-X-C motif chemokine ligand 8 Homo sapiens 202-206 28116315-0 2016 LPS Cooperates with Poly-L-Arginine to Promote IL-6 and IL-8 Release via the JNK Signaling Pathway in NCI-H292 Cells. polyarginine 20-35 C-X-C motif chemokine ligand 8 Homo sapiens 56-60 28116315-2 2016 Herein, we aimed to study the mechanism whereby poly-L-arginine (PLA) and lipopolysaccharide (LPS) can synergistically induce the release of interleukin-6 (IL-6) and IL-8 in NCI-H292 cells. polyarginine 48-63 C-X-C motif chemokine ligand 8 Homo sapiens 166-170 28116315-2 2016 Herein, we aimed to study the mechanism whereby poly-L-arginine (PLA) and lipopolysaccharide (LPS) can synergistically induce the release of interleukin-6 (IL-6) and IL-8 in NCI-H292 cells. polyarginine 65-68 C-X-C motif chemokine ligand 8 Homo sapiens 166-170 20711426-12 2010 CONCLUSIONS/SIGNIFICANCE: The results clearly demonstrate that damage to the bronchial epithelia by poly-L-arginine stimulates polarized IL-6 and IL-8 secretion. polyarginine 100-115 C-X-C motif chemokine ligand 8 Homo sapiens 146-150 19575800-8 2009 Poly-L-arginine enhanced the stimulus-induced IL-6 and IL-8 production, however, blocking arginine uptake and the enhanced IL-6 and IL-8 production appeared unrelated. polyarginine 0-15 C-X-C motif chemokine ligand 8 Homo sapiens 55-59 19575800-9 2009 The exaggerated IL-6 and IL-8 production due to arginine deficiency and to poly-L-arginine depend on a post-transcriptional and a transcriptional process, respectively. polyarginine 75-90 C-X-C motif chemokine ligand 8 Homo sapiens 25-29