PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22646928-0	2012	Heat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with fludarabine against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype.	fludarabine	78-89	CD40 ligand	Homo sapiens	145-150	
22072733-13	2012	CONCLUSION: We thus show that A771726 overcomes CD40L/IL-4-mediated resistance to fludarabine in CLL cells of untreated as well as clinically refractory CLL cells.	fludarabine	82-93	CD40 ligand	Homo sapiens	48-53	
20026377-6	2010	CD154 expression was found to have prognostic value for response to fludarabine in vivo and was associated with the development of autoimmune manifestations (odds ratio = 25; 95% confidence interval = 3.5-166.7; p < 0.001).	fludarabine	68-79	CD40 ligand	Homo sapiens	0-5	
20026377-7	2010	CONCLUSION: Our preliminary results suggest that CD154 expression in CLL patients, which may be induced by purine analogues, is associated with resistance to fludarabine and with development of autoimmune manifestations.	fludarabine	158-169	CD40 ligand	Homo sapiens	49-54	
9450802-5	1998	Exogenous CD40L rescued CLL cells from spontaneous apoptosis in a dose-dependent manner, and caused CLL cells to resist apoptosis induced by FasL or fludarabine.	fludarabine	149-160	CD40 ligand	Homo sapiens	10-15	
9450802-10	1998	Our results demonstrated that serum of patients with CLL contained elevated levels of biologically active soluble CD40L, and that CD40L can prolong survival of CLL cells and mediate their resistance to FasL and fludarabine in vitro.	fludarabine	211-222	CD40 ligand	Homo sapiens	130-135	
10674897-2	2000	In B chronic lymphocytic leukemia cells, the CD40/CD40L system has been shown to be effective in inhibiting the apoptotic response to fludarabine.	fludarabine	134-145	CD40 ligand	Homo sapiens	50-55	
35326640-4	2022	Co-culture on CD40L-expressing cells induced both canonical and non-canonical subunit expression in nuclear extracts, which promoted in vitro resistance against fludarabine and ABT-199 (venetoclax) but not CW15337.	fludarabine	161-172	CD40 ligand	Homo sapiens	14-19