PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9873474-1 1998 Actinomycin D, C2 and VII, cyclic peptides, inhibited Grb2 SH2 domain association (IC50 5-7 microM) with a phosphotyrosine containing peptide derived from the Shc protein (pTyr317). ptyr317 172-179 SHC adaptor protein 1 Homo sapiens 159-162 10891441-7 2000 Furthermore, a pTyr317 Shc phosphopeptide selectively recognized Grb2, Sos1, SHIP, and the p85 subunit of phosphatidylinositol 3" kinase from mast cells, as characterized by mass spectrometry. ptyr317 15-22 SHC adaptor protein 1 Homo sapiens 23-26 9360978-5 1997 Synthetic G1 peptide blocks Grb2 SH2 domain association (IC50 10-25 microM) with a 9-amino acid pTyr-containing peptide derived from the SHC protein (pTyr317). ptyr317 150-157 SHC adaptor protein 1 Homo sapiens 137-140