PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11696925-2	2001	The neuropathy-target-esterase (NTE) inhibition data were either obtained from the literature for a number of OP compounds or were determined experimentally for methamidophos, acephate, coumaphos and EPN.	methamidophos	161-174	patatin like phospholipase domain containing 6	Homo sapiens	32-35	
8492300-2	1993	However, it has been shown recently that certain N-unsubstituted organophosphoro-monoamidates (analogues of methamidophos) cause delayed neuropathy even though the inhibited NTE appeared not to have aged (Johnson et al.	methamidophos	108-121	patatin like phospholipase domain containing 6	Homo sapiens	174-177	
9486944-0	1997	Inhibition and aging of neuropathy target esterase by the stereoisomers of a phosphoramidate related to methamidophos.	methamidophos	104-117	patatin like phospholipase domain containing 6	Homo sapiens	24-50	
8211998-7	1993	In fact, mipafox and methamidophos as well as certain classic protective inhibitors such as carbamate and sulfonyl fluoride form an inhibited NTE which apparently does not age and yet produces neuropathy.	methamidophos	21-34	patatin like phospholipase domain containing 6	Homo sapiens	142-145	
8211998-16	1993	Moreover, the levels of NTE inhibited by methamidophos which can be promoted to neuropathy are lower than those required for classic protective chemicals and higher than those of classic neuropathic OPs.	methamidophos	41-54	patatin like phospholipase domain containing 6	Homo sapiens	24-27	
8211998-17	1993	This suggests that methamidophos has an intermediate position between the most and the least neuropathic NTE inhibitors.	methamidophos	19-32	patatin like phospholipase domain containing 6	Homo sapiens	105-108	
8393746-11	1993	NTE inhibitors have been ranked as full agonists (classic neuropathic inhibitors such as diisopropylfluorophosphate), partial agonists (protective or neuropathic, depending on the dose, such as methamidophos) and antagonists (protective, and neuropathic at the highest doses, such as phenylmethanesulfonyl fluoride).	methamidophos	194-207	patatin like phospholipase domain containing 6	Homo sapiens	0-3	
10447555-3	1999	Serial lymphocyte NTE (LNTE) was measured in a 16-year-old boy after acute poisoning with methamidophos for evaluation as a predictor of subsequent neuropathy.	methamidophos	90-103	patatin like phospholipase domain containing 6	Homo sapiens	18-21	
1781739-3	1991	The rate constants of inhibition (ka) and reactivation (k + 3) of human and hen brain AChE and NTE by methamidophos resolved optical isomers are here reported.	methamidophos	102-115	patatin like phospholipase domain containing 6	Homo sapiens	95-98	
22198100-7	2012	The (-)-methamidophos exhibited an IC(50) value approximately 6 times greater than that of the (+)-methamidophos for the lymphocyte NTE (LNTE) of hens, and (+)-methamidophos exhibited an IC(50) value approximately 7 times larger than that of the (-)-methamidophos for the hen brain AChE.	methamidophos	4-21	patatin like phospholipase domain containing 6	Homo sapiens	132-135	
2170085-7	1990	It is regarded that the pathogenesis of methamidophos-induced delayed polyneuropathy is the toxic effect produced by the "aging" of the phosphoryl-enzyme complex caused by the phosphorylation of a protein neurotoxic esterase (NTE) in the nervous system, and also is the autoimmuno disorder induced by the "aging" of the NTE being probably an immunological basis.	methamidophos	40-53	patatin like phospholipase domain containing 6	Homo sapiens	205-224	
2170085-7	1990	It is regarded that the pathogenesis of methamidophos-induced delayed polyneuropathy is the toxic effect produced by the "aging" of the phosphoryl-enzyme complex caused by the phosphorylation of a protein neurotoxic esterase (NTE) in the nervous system, and also is the autoimmuno disorder induced by the "aging" of the NTE being probably an immunological basis.	methamidophos	40-53	patatin like phospholipase domain containing 6	Homo sapiens	226-229	
2170085-7	1990	It is regarded that the pathogenesis of methamidophos-induced delayed polyneuropathy is the toxic effect produced by the "aging" of the phosphoryl-enzyme complex caused by the phosphorylation of a protein neurotoxic esterase (NTE) in the nervous system, and also is the autoimmuno disorder induced by the "aging" of the NTE being probably an immunological basis.	methamidophos	40-53	patatin like phospholipase domain containing 6	Homo sapiens	320-323	
22198100-7	2012	The (-)-methamidophos exhibited an IC(50) value approximately 6 times greater than that of the (+)-methamidophos for the lymphocyte NTE (LNTE) of hens, and (+)-methamidophos exhibited an IC(50) value approximately 7 times larger than that of the (-)-methamidophos for the hen brain AChE.	methamidophos	95-112	patatin like phospholipase domain containing 6	Homo sapiens	132-135