PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27803021-8 2017 Further studies with drugs containing a 2,4-diaminopyrimidine resulted in the discovery that the antibiotic trimethoprim also potently inhibits thiamine uptake mediated by THTR-1 (IC50 = 6.84 microM) and THTR-2 (IC50 = 5.56 microM). Trimethoprim 108-120 solute carrier family 19 member 3 Homo sapiens 204-210