PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35617047-3	2022	A central enzyme for generating dNTPs is ribonucleotide reductase, a critical mediator of de novo nucleotide synthesis composed of catalytic RRM1 subunits in complex with RRM2 or p53R2.	dntps	32-37	ribonucleotide reductase catalytic subunit M1	Homo sapiens	141-145	
33191406-1	2021	Ribonucleotide reductase (RNR), which is a heterodimeric tetramer composed of RRM1 and RRM2 subunits, is the rate-limiting enzyme in the synthesis of deoxyribonucleoside triphosphates (dNTPs) and essential for both DNA replication and the repair of DNA damage.	dntps	185-190	ribonucleotide reductase catalytic subunit M1	Homo sapiens	78-82	
32712628-6	2020	And this S559 phosphorylation of RRM1enhances RNR enzymatic activity and is required for maintaining sufficient dNTPs during normal DNA replication.	dntps	112-117	ribonucleotide reductase catalytic subunit M1	Homo sapiens	33-37