PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8675151-4	1996	Dose-dependent increases in superoxide release, interleukin-1 (IL-1) release, and, within a relatively narrow range, prostaglandin-E2 (PGE2) release were observed in opsonized zymosan (oz)-stimulated HHMphi derived from both cirrhotic and noncirrhotic patients.	Zymosan	176-183	interleukin 1 alpha	Homo sapiens	63-67	
8678906-2	1996	We demonstrate here that tenidap inhibits the zymosan-induced expression of both interleukin 1 and tumor necrosis factor alpha in macrophages, at the mRNA and protein levels.	Zymosan	46-53	interleukin 1 alpha	Homo sapiens	81-126	
8386286-2	1993	In our basic studies, HHM phi increased dose dependently the release of superoxide (O2-) and interleukin-1 (IL-1) when stimulated by opsonized zymosan, up to 1000 micrograms/dish.	Zymosan	143-150	interleukin 1 alpha	Homo sapiens	93-112	
8025949-10	1994	PB-PMNs in culture also showed mRNA expression for IL-1 alpha, IL-1 beta, and TNF alpha in a time- and dose-dependent manner, especially after stimulation with zymosan.	Zymosan	160-167	interleukin 1 alpha	Homo sapiens	51-61	
8131658-4	1993	The production of IL-1 was tested through human monocytes stimulated with zymosan and measured by ELISA method; the activity of IL-1 was measured by its effect on the proliferation of murine thymocytes.	Zymosan	74-81	interleukin 1 alpha	Homo sapiens	18-22	
2113649-9	1990	Zymosan or LPS stimulation of splenic cells from silicone- and PVC-loaded animals also secreted increased quantities of IL 1 as compared to controls.	Zymosan	0-7	interleukin 1 alpha	Homo sapiens	120-124	
2357213-2	1990	Using overnight adherent macrophages, stimulation with lipopolysaccharide or zymosan caused a time-dependent increase in IL-1 production.	Zymosan	77-84	interleukin 1 alpha	Homo sapiens	121-125	
2357213-3	1990	LTC4 was detected and preceded IL-1 production only in zymosan-treated macrophages.	Zymosan	55-62	interleukin 1 alpha	Homo sapiens	31-35	
2999234-4	1985	Similarly, IL 1 production by monocytes stimulated with the known IL 1 inducers muramyl dipeptide, silica, or zymosan was also enhanced by LTB4.	Zymosan	110-117	interleukin 1 alpha	Homo sapiens	11-15	
2801317-3	1989	E-5110 also inhibited the IL-1 generation induced by antigen-antibody complexes, opsonized zymosan and silica particles.	Zymosan	91-98	interleukin 1 alpha	Homo sapiens	26-30	
3500253-6	1987	Pretreatment of the neutrophils with IL-1a augmented neutrophil oxygen radical production induced by opsonized zymosan, and this synergistic effect was evident as early as 10 min after IL-1a was added to the neutrophil culture.	Zymosan	111-118	interleukin 1 alpha	Homo sapiens	37-42	
3500253-6	1987	Pretreatment of the neutrophils with IL-1a augmented neutrophil oxygen radical production induced by opsonized zymosan, and this synergistic effect was evident as early as 10 min after IL-1a was added to the neutrophil culture.	Zymosan	111-118	interleukin 1 alpha	Homo sapiens	185-190	
3500253-7	1987	Phagocytosis of opsonized particles by neutrophils, and degranulation induced by opsonized zymosan were also enhanced by IL-1a in a dose-dependent manner.	Zymosan	91-98	interleukin 1 alpha	Homo sapiens	121-126	
2999234-4	1985	Similarly, IL 1 production by monocytes stimulated with the known IL 1 inducers muramyl dipeptide, silica, or zymosan was also enhanced by LTB4.	Zymosan	110-117	interleukin 1 alpha	Homo sapiens	66-70	
6325057-2	1984	The addition of bacterial lipopolysaccharides (LPS), quartz silica particles, zymosan, or phorbol myristate acetate (PMA) enhanced 3 to 50 times the overall production and 25 to 2000 times the release of IL-1.	Zymosan	78-85	interleukin 1 alpha	Homo sapiens	204-208	
6325057-4	1984	During the same period of time, the addition of silica particles or PMA had clearly less effect while the addition of LPS or zymosan produced high levels of intracellular IL-1 but only a modest release of it.	Zymosan	125-132	interleukin 1 alpha	Homo sapiens	171-175