PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23842856-13	2013	Polymorphisms in the estrogen receptor-1 and UGT2B15 may be associated with tamoxifen efficacy, but these findings need replication.	Tamoxifen	76-85	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	45-52	
26495850-0	2015	Correction: Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.	Tamoxifen	90-99	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	67-74	
26176234-0	2015	Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.	Tamoxifen	78-87	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	55-62	
26176234-4	2015	This descriptive study examines correlations between concentrations of tamoxifen"s glucuronide metabolites and genotypes UGT1A4 Pro24Thr, UGT1A4 Leu48Val, UGT2B7 His268Tyr, UGT2B15 Asp85YTyr UGT2B15 Lys523Thr and UGT2B17del in 132 patients with estrogen receptor-positive breast cancer under treatment with tamoxifen.	Tamoxifen	71-80	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	173-180	
26176234-4	2015	This descriptive study examines correlations between concentrations of tamoxifen"s glucuronide metabolites and genotypes UGT1A4 Pro24Thr, UGT1A4 Leu48Val, UGT2B7 His268Tyr, UGT2B15 Asp85YTyr UGT2B15 Lys523Thr and UGT2B17del in 132 patients with estrogen receptor-positive breast cancer under treatment with tamoxifen.	Tamoxifen	71-80	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	191-198	
25795461-0	2015	Induction of UDP-glucuronosyltransferase 2B15 gene expression by the major active metabolites of tamoxifen, 4-hydroxytamoxifen and endoxifen, in breast cancer cells.	Tamoxifen	97-106	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	13-45	
25795461-3	2015	Furthermore, we found that, similar to 17beta-estradiol, 4-OHTAM and endoxifen (another major active TAM metabolite) elevated UGT2B15 mRNA levels, and that this stimulation was significantly abrogated by fulvestrant.	Tamoxifen	61-64	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	126-133	
23951298-12	2013	In the tamoxifen-treated subgroup, poor prognosis was related to the combined presence of ESR1 PvuII wt/wt and UGT2B15wt/wt or wt/*2 genotype.	Tamoxifen	7-16	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	111-118	
21152250-5	2010	We used TaqMan assays to determine the genotypes of three enzyme variants hypothesized to modify tamoxifen effectiveness, ie, CYP2D6*4, UGT2B15*2, and UGT1A8*2.	Tamoxifen	97-106	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	136-143	
15952058-4	2005	We also examined whether the combination of variant alleles in SULT1A1 and UGT2B15 had more of an impact on overall survival in tamoxifen-treated patients than when the genes were examined separately.	Tamoxifen	128-137	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	75-82	
17244352-11	2007	The significantly improved RFS with prolonged tamoxifen treatment in CYP3A5*3 homozygotes was also seen in a multivariate Cox model (HR = 0.13, CI = 0.02 to 0.86, P = 0.03), whereas no differences could be seen for CYP2D6, SULT1A1 and UGT2B15.	Tamoxifen	46-55	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	235-242	
15952058-8	2005	Tamoxifen-treated patients with UGT2B15 high activity genotypes had increased risk of recurrence and poorer survival.	Tamoxifen	0-9	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	32-39	
15135306-7	2004	Only UGT1A4 catalyzed the N-linked glucuronidation of TAM among recombinant UGTs (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B4, UGT2B7, UGT2B15, and UGT2B17) expressed in insect cells.	Tamoxifen	54-57	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	138-145	
34899282-10	2021	Our results suggest that the response to TAM treatment in ER + BC patients might be associated with the presence of the studied genetic variants in UGT2B15, CYP3A5, SULT1A1 and ESRA genes.	Tamoxifen	41-44	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	148-155	
33503040-11	2021	Whereas those disrupting SULT1A1 and UGT2B15 seem to correlate with good clinical response to tamoxifen.	Tamoxifen	94-103	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	37-44