PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 932031-6 1976 In contrast, 1.0 muM propranolol essentially completely inhibited the 8-fold stimulation of 1.0 muM epinephrine but had no effect on either basal or adenosine-stimulated activity. Epinephrine 100-111 latexin Homo sapiens 17-20 7258729-3 1981 We found that 2 muM of ADP, and 9.1 and 22.7 muM of adrenalin induced statistically significant increases in nondissociative patterns of platelet aggregation in the patient group. Epinephrine 52-61 latexin Homo sapiens 45-48 6257762-5 1981 Cells or cell membranes were incubated with epinephrine (10 muM) alone and in combination with the antagonists yohimbine (alpha-2) and prazosin (alpha-1). Epinephrine 44-55 latexin Homo sapiens 60-63 6127588-4 1982 Alpha-2 adrenergic activation, achieved with 10 muM epinephrine and 30 muM propranolol, significantly inhibited forskolin-stimulated cyclic AMP accumulation and glycerol release, shifting the dose-response curves to the right. Epinephrine 52-63 latexin Homo sapiens 48-51 956686-6 1976 The mean threshold concentration of epinephrine necessary for aggregation of normal platelets (4.2 muM) was not significatnly increased with clofibrate (10 muM) but was markedly elevated with halofenate (245 muM; p less than 0.001). Epinephrine 36-47 latexin Homo sapiens 99-102 932031-6 1976 In contrast, 1.0 muM propranolol essentially completely inhibited the 8-fold stimulation of 1.0 muM epinephrine but had no effect on either basal or adenosine-stimulated activity. Epinephrine 100-111 latexin Homo sapiens 96-99 818909-7 1976 Epinephrine (40 muM), prostaglandin E1 (7 muM), or serotonin (2 muM) added before fixation caused slight to moderate inhibition but always less than ADP. Epinephrine 0-11 latexin Homo sapiens 16-19 31635605-4 2020 The cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods showed a wide linear response to a concentration range, from 1.71 to 55.00 muM, and the epinephrine detection limit for this sensing system was found to be 1.334 muM. Epinephrine 165-176 latexin Homo sapiens 152-155 4349947-10 1973 Combinations of 1 muM hydrocortisone and 1 muM epinephrine were sometimes additive or synergistic but in many instances higher glucocorticoid concentrations were needed to obtain augmentation of the catecholamine response. Epinephrine 47-58 latexin Homo sapiens 43-46 1247673-1 1976 In the presence of EDTA soluble antioxidants (1 muM reduced glutathion, 3 muM cystein, 1 muM ascorbic acid) inhibited the autoxidation of epinephrine at pH 10.2; as to alpha-tocopherol (40 muM) and the oxidative forms of these antioxidants - they were ineffective. Epinephrine 138-149 latexin Homo sapiens 48-51 1247673-1 1976 In the presence of EDTA soluble antioxidants (1 muM reduced glutathion, 3 muM cystein, 1 muM ascorbic acid) inhibited the autoxidation of epinephrine at pH 10.2; as to alpha-tocopherol (40 muM) and the oxidative forms of these antioxidants - they were ineffective. Epinephrine 138-149 latexin Homo sapiens 74-77 1247673-1 1976 In the presence of EDTA soluble antioxidants (1 muM reduced glutathion, 3 muM cystein, 1 muM ascorbic acid) inhibited the autoxidation of epinephrine at pH 10.2; as to alpha-tocopherol (40 muM) and the oxidative forms of these antioxidants - they were ineffective. Epinephrine 138-149 latexin Homo sapiens 74-77 1247673-1 1976 In the presence of EDTA soluble antioxidants (1 muM reduced glutathion, 3 muM cystein, 1 muM ascorbic acid) inhibited the autoxidation of epinephrine at pH 10.2; as to alpha-tocopherol (40 muM) and the oxidative forms of these antioxidants - they were ineffective. Epinephrine 138-149 latexin Homo sapiens 74-77 168084-4 1975 Adipocytes of women at the end of pregnancy exhibited higher rates of lipolysis in response to adrenaline (1.5 - 15 muM) plus phentolamine (13 muM) than those of non-pregnant women or those in early pregnancy. Epinephrine 95-105 latexin Homo sapiens 116-119 168084-12 1975 Cell levels of cyclic AMP rose after incubation with adrenaline (6 muM) plus phentolamine or adrenaline (15 muM) plus phentolamine plus caffeine (1 mM) but were similar in all four groups of women. Epinephrine 53-63 latexin Homo sapiens 67-70 168084-12 1975 Cell levels of cyclic AMP rose after incubation with adrenaline (6 muM) plus phentolamine or adrenaline (15 muM) plus phentolamine plus caffeine (1 mM) but were similar in all four groups of women. Epinephrine 93-103 latexin Homo sapiens 108-111 1231964-2 1975 The response of platelet-rich plasma to 0.1, 1 and 10 muM of ADP and 1 and 10 muM of epinephrine were tested in a Chrono-Log aggregometer. Epinephrine 85-96 latexin Homo sapiens 78-81 1225939-3 1975 Epinephrine (10 muM) stimulated adenylate cyclase activity and this effect was slightly enhanced by phentolamine. Epinephrine 0-11 latexin Homo sapiens 16-19 31635605-4 2020 The cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods showed a wide linear response to a concentration range, from 1.71 to 55.00 muM, and the epinephrine detection limit for this sensing system was found to be 1.334 muM. Epinephrine 165-176 latexin Homo sapiens 239-242 32047262-8 2020 We found that addition of adrenaline (10 muM) significantly improved GA A protection in PC12 cells. Epinephrine 26-36 latexin Homo sapiens 41-44 30785148-7 2019 This electrochemical sensor displayed a high selectivity owing to the specific imprinted cavities for adrenaline and worked well over a wide linear concentration range of adrenaline between 0.0015 and 50 muM with a detection limit (LOD) of 0.25 nM and good reproducibility and stability. Epinephrine 102-112 latexin Homo sapiens 204-207 32043995-7 2020 The detection limits of noradrenaline, adrenaline, and dopamine were 0.1, 0.1, and 0.2 muM, respectively. Epinephrine 27-37 latexin Homo sapiens 87-90 31421743-5 2019 It was observed that higher concentrations of adrenaline (1 and 10 muM) induced DNA damage in the obese, prediabetic and diabetic groups. Epinephrine 46-56 latexin Homo sapiens 67-70 30785148-7 2019 This electrochemical sensor displayed a high selectivity owing to the specific imprinted cavities for adrenaline and worked well over a wide linear concentration range of adrenaline between 0.0015 and 50 muM with a detection limit (LOD) of 0.25 nM and good reproducibility and stability. Epinephrine 171-181 latexin Homo sapiens 204-207 29482394-5 2018 The most potent compound 3, effectively inhibited the platelet-aggregation induced both by collagen and ADP/adrenaline with IC50 of 26.9 muM and 20.5 muM respectively. Epinephrine 108-118 latexin Homo sapiens 137-140 29482394-5 2018 The most potent compound 3, effectively inhibited the platelet-aggregation induced both by collagen and ADP/adrenaline with IC50 of 26.9 muM and 20.5 muM respectively. Epinephrine 108-118 latexin Homo sapiens 150-153 29753967-6 2018 By taking advantage of this fact, a sensitive probe was designed for determination of dopamine, adrenaline and noradrenaline with a limit of detection of 0.07, 0.60 and 0.01 muM, respectively. Epinephrine 96-106 latexin Homo sapiens 174-177 24680993-8 2014 Moreover, DeHE (0.1 and 0.3 muM) suppressed delayed afterdepolarizations and aftercontractions, induced by epinephrine and high [Ca(2+)]o in atria. Epinephrine 107-118 latexin Homo sapiens 28-31 29704250-9 2018 Using this system with a gold microelectrode, dopamine, and epinephrine could be quantified within the concentration range of 1-500 muM and detected at a concentration of 0.3 muM. Epinephrine 60-71 latexin Homo sapiens 132-135 29704250-9 2018 Using this system with a gold microelectrode, dopamine, and epinephrine could be quantified within the concentration range of 1-500 muM and detected at a concentration of 0.3 muM. Epinephrine 60-71 latexin Homo sapiens 175-178 25172298-3 2015 In cytogenetic tests, six experimental concentrations of adrenaline were used in a range from 0.01-500 muM. Epinephrine 57-67 latexin Homo sapiens 103-106 25172298-5 2015 However, at four highest concentrations of adrenaline (5 muM, 50 muM, 150 muM and 300 muM) we observed a decreased mitotic index and cell-cycle delay. Epinephrine 43-53 latexin Homo sapiens 57-60 25172298-5 2015 However, at four highest concentrations of adrenaline (5 muM, 50 muM, 150 muM and 300 muM) we observed a decreased mitotic index and cell-cycle delay. Epinephrine 43-53 latexin Homo sapiens 65-68 25172298-5 2015 However, at four highest concentrations of adrenaline (5 muM, 50 muM, 150 muM and 300 muM) we observed a decreased mitotic index and cell-cycle delay. Epinephrine 43-53 latexin Homo sapiens 65-68 25172298-5 2015 However, at four highest concentrations of adrenaline (5 muM, 50 muM, 150 muM and 300 muM) we observed a decreased mitotic index and cell-cycle delay. Epinephrine 43-53 latexin Homo sapiens 65-68 25172298-6 2015 In addition, in the Comet assay we used adrenaline in a range from 0.0005-500 muM, at two treatment times: 15 min or 60 min. Epinephrine 40-50 latexin Homo sapiens 78-81 25243022-7 2014 Platelets were treated with ADP and epinephrine in decreasing concentrations of 2.34, 1.17, and 0.58 muM, as well as, 11.0, 1.1, and 0.55 muM, respectively. Epinephrine 36-47 latexin Homo sapiens 101-104 25243022-10 2014 There was a significant difference in the detection of increased platelet aggregation using 11.0 muM and 0.55 muM epinephrine and 0.58 muM ADP. Epinephrine 114-125 latexin Homo sapiens 110-113 25243022-10 2014 There was a significant difference in the detection of increased platelet aggregation using 11.0 muM and 0.55 muM epinephrine and 0.58 muM ADP. Epinephrine 114-125 latexin Homo sapiens 110-113 25243022-11 2014 With both agonists, ROC analysis showed an area under the curve of >0.8 for 11.0 muM epinephrine and 2.34 muM ADP. Epinephrine 88-99 latexin Homo sapiens 84-87 25243022-12 2014 However, for MS patients, 11.0 muM epinephrine had a slightly better diagnostic efficiency than 2.34 muM ADP. Epinephrine 35-46 latexin Homo sapiens 31-34 25243022-13 2014 CONCLUSIONS: It was found that 11.0 muM epinephrine and 2.34 muM ADP detected better platelet aggregation in patients with MS than in healthy subject. Epinephrine 40-51 latexin Homo sapiens 36-39 17663734-7 2007 A limited genotype analysis demonstrated that the C825T polymorphism of GNB3 was associated with the platelet aggregation response to 2 muM epinephrine, but the effect differed by race. Epinephrine 140-151 latexin Homo sapiens 136-139