PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23010500-10 2012 Moreover, during adrenaline infusion the leptin release from leg skeletal muscle was strongly suppressed (20.5 +- 7.9 ng min(-1), p<0.017), whereas the release from fat was unaltered. Epinephrine 17-27 CD59 molecule (CD59 blood group) Homo sapiens 121-127 22508204-6 2012 Adrenaline (mean dose: 0.06 mug/kg x min-1) was required in seven patients from Group B but in none of the Group A patients on initial separation from CPB (P< 0.05). Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 37-42 20618356-3 2010 infusion of adrenaline (0.1 nmol kg-1 min-1) or placebo. Epinephrine 12-22 CD59 molecule (CD59 blood group) Homo sapiens 38-43 16424800-3 2006 Therefore, we quantified the hemodynamic response to infusion of adrenaline (0.04, 0.06, and 0.08 microg x kg(-1) x min(-1) for 20 minutes each) in 8 healthy men and 8 healthy premenopausal women. Epinephrine 65-75 CD59 molecule (CD59 blood group) Homo sapiens 116-122 17051993-10 2006 Epinephrine at 0.005-0.02 microg x kg(-1) x min(-1) was infused continuously to maintain his blood pressure. Epinephrine 0-11 CD59 molecule (CD59 blood group) Homo sapiens 44-50 15955567-4 2005 CD14 expression in macrophages derived in vitro from CD59(+) cells following BI/S was significantly increased by epinephrine and this change was blocked by beta(2)-adrenergic receptor antagonist. Epinephrine 113-124 CD59 molecule (CD59 blood group) Homo sapiens 53-57 9536919-2 1998 In order to evaluate factors influencing thermogenesis in obesity, energy expenditure was measured before and during an adrenaline infusion (25 ng min-1 kg-1 ideal body weight for 30 min) in 22 obese females. Epinephrine 120-130 CD59 molecule (CD59 blood group) Homo sapiens 147-157 10651786-8 2000 After baseline measurements, adrenaline was infused at a rate of 0.3 nmol kg-1 min-1. Epinephrine 29-39 CD59 molecule (CD59 blood group) Homo sapiens 79-84 10651786-10 2000 During infusion of adrenaline, blood flow and lactate output increased significantly more in the non-dominant arm (8.12 +/- 1.24 versus 6.45 +/- 1.19 ml 100 g-1 min-1) and (2.99 +/- 0.60 versus 1.83 +/- 0.43 micromol 100 g-1 min-1). Epinephrine 19-29 CD59 molecule (CD59 blood group) Homo sapiens 161-166 10651786-10 2000 During infusion of adrenaline, blood flow and lactate output increased significantly more in the non-dominant arm (8.12 +/- 1.24 versus 6.45 +/- 1.19 ml 100 g-1 min-1) and (2.99 +/- 0.60 versus 1.83 +/- 0.43 micromol 100 g-1 min-1). Epinephrine 19-29 CD59 molecule (CD59 blood group) Homo sapiens 225-230 10651786-11 2000 Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 136-141 10651786-11 2000 Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 193-198 10651786-11 2000 Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 193-198 12477685-4 2002 RESULTS: Infusion rates up to 0.05 microg x kg(-1) x min(-1) were effective against agitation and achieved a good degree of adaption to the respirator in all patients (RSS 2 or more and CSRR 3 or less); BIS decreased significantly; respiratory and circulatory variables were unaffected; mean plasma epinephrine levels decreased. Epinephrine 299-310 CD59 molecule (CD59 blood group) Homo sapiens 53-59 11353933-14 2001 Epinephrine increased hepatic arterial flow at 0.2 microg kg-1 min-1; dopamine had no effect on hepatic arterial flow at any dose. Epinephrine 0-11 CD59 molecule (CD59 blood group) Homo sapiens 63-68 9180633-4 1997 The increased arterial plasma epinephrine levels appeared to be due to a higher total body epinephrine spillover rate in the hypertensive subjects (0.23 +/- 0.02 nmol.min-1.m-2) than the normotensive subjects (0.18 +/- 0.01) (P < .05) and not to a decreased plasma clearance of epinephrine. Epinephrine 30-41 CD59 molecule (CD59 blood group) Homo sapiens 167-172 9429045-6 1997 She required an epinephrine infusion of 0.4 microgram.kg-1.min-1 and prolonged ICU admission. Epinephrine 16-27 CD59 molecule (CD59 blood group) Homo sapiens 59-64 8737076-3 1996 Dopamine, noradrenaline and adrenaline enter the red blood cell by a similar process, which shows saturation kinetics with Vmax values of 0.54 +/- 0.12, 0.48 +/- 0.08 and 0.63 +/- 0.13 mumol (1 cells)-1 min-1, respectively, and K(m) values of 15.62 +/- 1.19, 5.81 +/- 1.19 and 12.00 +/- 2.97 nM, respectively. Epinephrine 13-23 CD59 molecule (CD59 blood group) Homo sapiens 203-208 8809522-9 1996 (2) In mode 10/60 s, heart rate and systolic blood pressure increased significantly (82 +/- 4 --> 85 +/- 4 beats.min-1; 124 +/- 5 --> 134 +/- 5 mmHg; P < 0.05 each), while in mode 15/60 s catecholamines increased significantly (norepinephrine 0.804 +/- 0.089 --> 1.135 +/- 0.094 nmol.l-1; P < 0.008; epinephrine 0.136 +/- 0.012 --> 0.193 +/- 0.019 nmol.l-1; P < 0.005). Epinephrine 240-251 CD59 molecule (CD59 blood group) Homo sapiens 116-121 8931644-1 1996 The rate of protein synthesis was assessed in muscle, lymphocytes, and albumin in healthy volunteers administered an infusion of 6.0 micrograms cortisol +3.0 ng glucagon +0.5 nmol epinephrine min-1.kg-1. Epinephrine 180-191 CD59 molecule (CD59 blood group) Homo sapiens 192-197 8983867-2 1996 Adrenaline was infused at a rate of 25 ng min-1 kg-1 into seven healthy volunteers and its effects on adipose tissue were studied by microdialysis. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 42-52 7572705-6 1995 Each subject was studied in the basal state and during a 1-h infusion of epinephrine (0.015 microgram kg(-1 min(-1) after 84 h of total energy restriction and after 84 h of carbohydrate restriction (12 h after the final lipid infusion). Epinephrine 73-84 CD59 molecule (CD59 blood group) Homo sapiens 108-114 8866876-8 1996 In another trial (120 min duration), adrenaline was infused (AI) at 0.1 microgram kg-1 min-1 and plasma catecholamine levels were elevated 6 pmol ml-1 above SI during the 60-120 min period. Epinephrine 37-47 CD59 molecule (CD59 blood group) Homo sapiens 87-92 7593645-9 1995 Epinephrine infusion, which increased plasma epinephrine to levels observed during hypoglycemia (3722 +/- 453 pmol/liter) increased renal glucose release nearly twofold (5.2 +/- 0.5 vs 2.8 +/- 0.1 mol.kg-1.min-1, P = 0.01) so that at the end of the infusion, renal glucose release accounted for 40.3 +/- 5.5% of systemic glucose appearance and essentially all of the increase in systemic glucose appearance. Epinephrine 0-11 CD59 molecule (CD59 blood group) Homo sapiens 206-211 8267422-5 1993 Epinephrine (mean dose, 0.07 +/- 0.02 micrograms.kg-1.min-1) was administered via the central venous route, then via the left atrium, then via the central venous route again. Epinephrine 0-11 CD59 molecule (CD59 blood group) Homo sapiens 54-59 7736695-2 1995 We tested the effect of intravenous adrenaline at 0.55-1.10 nmol min-1 kg-1 (for 3-8 min, at 7-10 min post bypass; n = 7) on both microaggregation in hirudinized whole blood, using platelet counting, and macroaggregation in platelet-rich plasma, using optical aggregometry. Epinephrine 36-46 CD59 molecule (CD59 blood group) Homo sapiens 65-75 7729444-1 1995 Adrenaline infusion of 0.1 microgram.kg-1.min-1 in healthy volunteers results in an increase of hepatic glucose production, an increase of the absolute number of occupied beta-adrenoceptors and specific changes in metabolism. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 42-47 1425612-2 1992 Adrenaline was administered at five infusion rates (0.01-0.2 micrograms kg-1 min-1) in an escalating sequence to eight volunteers. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 77-82 1443116-2 1992 After a control period, epinephrine was infused at rates of 0.2 and 0.4 nmol.kg-1 x min-1. Epinephrine 24-35 CD59 molecule (CD59 blood group) Homo sapiens 84-89 1859754-5 1991 infusions of adrenaline (1-5 micrograms min-1). Epinephrine 13-23 CD59 molecule (CD59 blood group) Homo sapiens 40-45 1655647-3 1991 To this end, two strictly standardized mental stress tests were performed in 14 normotensive men during and 1 hour after double-blind infusion of epinephrine (50 ng x kg-1 x min-1) or placebo given in random order. Epinephrine 146-157 CD59 molecule (CD59 blood group) Homo sapiens 174-179 2582730-7 1989 adrenaline infusion (0.02 microgram min-1 kg-1 body weight). Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 36-41 2031819-12 1991 Defining a positive result to a test dose as an increase in HR of greater than 10 beat min-1, the sensitivity of the adrenaline test dose was 83 (5.5)% in the saline group and 91 (3.5)% in the atropine group (ns). Epinephrine 117-127 CD59 molecule (CD59 blood group) Homo sapiens 87-92 2176947-11 1990 The plasma adrenaline concentration rose significantly (P less than 0.01), but only transiently, during dopamine infusion at a rate of 2 micrograms min-1 kg-1. Epinephrine 11-21 CD59 molecule (CD59 blood group) Homo sapiens 148-158 2558700-9 1989 Adrenaline infusion raised venous plasma adrenaline levels to 4-5 nmol l-1, increased heart rate by 14 +/- 3 beats min-1 and plasma cyclic AMP by 17 +/- 3 nmol l-1, and decreased diastolic blood pressure by 15 +/- 5 mm Hg. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 115-120 2582730-9 1989 Whole body oxygen uptake, carbon dioxide production, heart rate and plasma concentrations of free fatty acids (FFA) increased while the mean arterial pressure decreased significantly in response to adrenaline infusion at 0.02 microgram kg-1 min-1 in both weight-losing and weight-stable patients. Epinephrine 198-208 CD59 molecule (CD59 blood group) Homo sapiens 241-246 2582730-10 1989 Adrenaline at 0.005 microgram kg-1 min-1 increased plasma FFA levels by 19% (P less than 0.05) in weight-losing patients while no significant alteration was observed in well-nourished patients. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 35-40 2582730-11 1989 Adrenaline infusion at 0.02 microgram kg-1 min-1 decreased the mean arterial blood pressure and stimulated respiratory gas exchange and heart rate significantly more in weight-losing than in weight-stable patients. Epinephrine 0-10 CD59 molecule (CD59 blood group) Homo sapiens 43-48 3316041-4 1987 Catecholamine excretion in urine (adrenaline + noradrenaline) on average was 252.3 +/- 77.9 ng min-1 during car racing and 121.9 +/- 37.3 ng min-1 during exhaustive ergometry (n = 10). Epinephrine 34-44 CD59 molecule (CD59 blood group) Homo sapiens 95-100 3197373-2 1988 On two separate occasions, at least 1 week apart, seven young healthy male subjects received intravenous infusions of either adrenaline [0.27 nmol (50 ng) min-1 kg-1] or saline (154 mmol/l NaCl), plus ascorbic acid (5.68 mmol/l), over 30 min. Epinephrine 125-135 CD59 molecule (CD59 blood group) Homo sapiens 155-165 2657547-3 1989 The total dose and the mg min-1 dose of bupivacaine was significantly less following epinephrine-morphine pretreatment than the dose required when only bupivacaine was used for pain relief. Epinephrine 85-96 CD59 molecule (CD59 blood group) Homo sapiens 26-31 3592145-8 1987 Subcutaneously administered adrenaline caused within 5 min a significant increase of plasma adrenaline level (from 1.0 +/- 0.2 to peak of 6.5 +/- 1.2 nM) which gradually decreased during 2 h. This mode of adrenaline administration increased the systolic blood pressure by a maximum of 11 +/- 3.5 mmHg, heart rate by 9 +/- 2.2 beats X min-1, tremor ratio by 4 +/- 0.6 and reduced the diastolic blood pressure by 18 +/- 4.7 mmHg. Epinephrine 28-38 CD59 molecule (CD59 blood group) Homo sapiens 334-339 3592145-8 1987 Subcutaneously administered adrenaline caused within 5 min a significant increase of plasma adrenaline level (from 1.0 +/- 0.2 to peak of 6.5 +/- 1.2 nM) which gradually decreased during 2 h. This mode of adrenaline administration increased the systolic blood pressure by a maximum of 11 +/- 3.5 mmHg, heart rate by 9 +/- 2.2 beats X min-1, tremor ratio by 4 +/- 0.6 and reduced the diastolic blood pressure by 18 +/- 4.7 mmHg. Epinephrine 92-102 CD59 molecule (CD59 blood group) Homo sapiens 334-339 3592145-8 1987 Subcutaneously administered adrenaline caused within 5 min a significant increase of plasma adrenaline level (from 1.0 +/- 0.2 to peak of 6.5 +/- 1.2 nM) which gradually decreased during 2 h. This mode of adrenaline administration increased the systolic blood pressure by a maximum of 11 +/- 3.5 mmHg, heart rate by 9 +/- 2.2 beats X min-1, tremor ratio by 4 +/- 0.6 and reduced the diastolic blood pressure by 18 +/- 4.7 mmHg. Epinephrine 92-102 CD59 molecule (CD59 blood group) Homo sapiens 334-339 3582518-6 1987 Theophylline increased the hypokalaemia, tachycardia and rise in systolic blood pressure which occurs in response to intravenous infusion of doses of L-adrenaline (0.02-0.06 microgram kg-1 min-1). Epinephrine 150-162 CD59 molecule (CD59 blood group) Homo sapiens 189-194 6690194-2 1984 During a second study, adrenaline was infused intravenously in six resting subjects at a rate of 0.025 micrograms min-1 kg-1. Epinephrine 23-33 CD59 molecule (CD59 blood group) Homo sapiens 114-124 2881786-1 1986 The effects of direct adrenergic stimulation, achieved by 60-min adrenaline infusion (0.1-0.2 microgram kg-1 min-1), on thromboxane B2 (TxB2) production by platelets in whole blood ex vivo and on ADP-induced platelet aggregation were studied in seven healthy male volunteers. Epinephrine 65-75 CD59 molecule (CD59 blood group) Homo sapiens 109-114 2868743-6 1985 In Study 2 adrenaline 0.05 micrograms kg-1 min-1 was infused for 80 min preceded by either idazoxan or vehicle. Epinephrine 11-21 CD59 molecule (CD59 blood group) Homo sapiens 43-48 6995479-5 1980 At steady-state plasma epinephrine concentrations of 24-74 pg/ml, values overlapping the basal normal range, the mean (+/-SE) plasma metabolic clearance rate of epinephrine was 52 +/- 4 ml x min-1 x kg-1; this value rose to 89 +/- 6 ml x min-1 x kg-1 (P less than 0.01) at steady-state epinephrine concentrations of 90-1,020 pg/ml. Epinephrine 161-172 CD59 molecule (CD59 blood group) Homo sapiens 191-196 6995479-5 1980 At steady-state plasma epinephrine concentrations of 24-74 pg/ml, values overlapping the basal normal range, the mean (+/-SE) plasma metabolic clearance rate of epinephrine was 52 +/- 4 ml x min-1 x kg-1; this value rose to 89 +/- 6 ml x min-1 x kg-1 (P less than 0.01) at steady-state epinephrine concentrations of 90-1,020 pg/ml. Epinephrine 161-172 CD59 molecule (CD59 blood group) Homo sapiens 191-196 580191-3 1978 The constants characterising this inhibition, the bimolecular rate ka (51.8 M-1 min-1 for epinephrine and 15.9 M-1 min-1 for norepinephrine) and the enzyme inhibitor dissociation constant (8.52 mM for epinephrine and 12.2 mM norepinephrine) were determined. Epinephrine 90-101 CD59 molecule (CD59 blood group) Homo sapiens 80-85 6831836-5 1983 On a separate occasion, two doses of L-adrenaline (0.025 micrograms min-1 kg-1 and 0.05 micrograms min-1 kg-1) were infused in the same subjects at rest to produce two mean plasma levels similar to those found on exercise. Epinephrine 37-49 CD59 molecule (CD59 blood group) Homo sapiens 68-84 7052338-1 1980 1 The effects of adrenoceptor blocking drugs on the metabolic responses to adrenaline infusion (1 microgram kg-1 min-1) have been studied in the anaesthetized, fasted cat. Epinephrine 75-85 CD59 molecule (CD59 blood group) Homo sapiens 113-118 7052338-3 1980 3 Phentolamine infusion, at a rate (15 micrograms kg-1 min-1 after a priming dose of 2.5 mg/kg) which reversed the pressor effect of adrenaline, reduced but did not abolish adrenaline-induced hyperglycaemia. Epinephrine 133-143 CD59 molecule (CD59 blood group) Homo sapiens 55-60