PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29080699-3	2018	CYP enzymes, previously identified as arachidonic acid (20:4n-6; AA) epoxygenases, accept eicosapentaenoic acid (20:5n-3; EPA) and docosahexaenoic acid (22:6n-3; DHA), the major fish oil n-3 LC-PUFAs, as efficient alternative substrates.	dehydroacetic acid	162-165	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-3	
29080699-4	2018	In humans and rodents, dietary EPA/DHA supplementation causes a profound shift of the endogenous CYP-eicosanoid profile from AA- to EPA- and DHA-derived metabolites, increasing, in particular, the plasma and tissue levels of 17,18-epoxyeicosatetraenoic acid (17,18-EEQ) and 19,20-epoxydocosapentaenoic acid (19,20-EDP).	dehydroacetic acid	35-38	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	97-100	
29080699-4	2018	In humans and rodents, dietary EPA/DHA supplementation causes a profound shift of the endogenous CYP-eicosanoid profile from AA- to EPA- and DHA-derived metabolites, increasing, in particular, the plasma and tissue levels of 17,18-epoxyeicosatetraenoic acid (17,18-EEQ) and 19,20-epoxydocosapentaenoic acid (19,20-EDP).	dehydroacetic acid	141-144	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	97-100	
24634501-2	2014	CYP enzymes also accept EPA and DHA to yield more potent vasodilatory and potentially anti-arrhythmic metabolites, suggesting that the endogenous CYP-eicosanoid profile can be favorably shifted by dietary omega-3 fatty acids.	dehydroacetic acid	32-35	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-3	
24634501-2	2014	CYP enzymes also accept EPA and DHA to yield more potent vasodilatory and potentially anti-arrhythmic metabolites, suggesting that the endogenous CYP-eicosanoid profile can be favorably shifted by dietary omega-3 fatty acids.	dehydroacetic acid	32-35	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	146-149	
24634501-5	2014	The metabolite/precursor fatty acid ratios indicated that CYP epoxygenases metabolized EPA with an 8.6-fold higher efficiency and DHA with a 2.2-fold higher efficiency than AA.	dehydroacetic acid	130-133	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	58-61	
24634501-7	2014	We propose that CYP-dependent epoxy-metabolites of EPA and DHA may function as mediators of the vasodilatory and cardioprotective effects of omega-3 fatty acids and could serve as biomarkers in clinical studies investigating the cardiovascular effects of EPA/DHA supplementation.	dehydroacetic acid	59-62	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	16-19	
24634501-7	2014	We propose that CYP-dependent epoxy-metabolites of EPA and DHA may function as mediators of the vasodilatory and cardioprotective effects of omega-3 fatty acids and could serve as biomarkers in clinical studies investigating the cardiovascular effects of EPA/DHA supplementation.	dehydroacetic acid	259-262	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	16-19