PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15357021-1 2004 The activity of delta6- and delta5-desaturase, enzymes required for the synthesis of AA and DHA, are impaired in human and experimental diabetes. dehydroacetic acid 92-95 fatty acid desaturase 2 Homo sapiens 16-45 16441943-7 2006 However, up-regulation of the conversion of EPA to DHA has also been suggested, as a result of the actions of oestrogen on Delta6-desaturase, and may be of particular importance in maintaining adequate provision of DHA in pregnancy. dehydroacetic acid 51-54 fatty acid desaturase 2 Homo sapiens 129-140 26078250-8 2015 MDI score was associated with a FADS2 index (DHA:EPA ratio) but not genotype (Adjusted R-square= 0.043). dehydroacetic acid 45-48 fatty acid desaturase 2 Homo sapiens 32-37 22585914-4 2012 Activity of the delta-6-desaturase and the delta-5-desaturase necessary for DHA synthesis is decreased by protein deprivation. dehydroacetic acid 76-79 fatty acid desaturase 2 Homo sapiens 16-34 28598979-9 2017 Among minor allele carriers of FADS2 and ELOVL2 SNPs, overweight/obese women showed higher DHA:EPA index than the normal-weight group; however, they did not present higher DHA concentrations than the normal-weight women. dehydroacetic acid 91-94 fatty acid desaturase 2 Homo sapiens 31-36 25550171-4 2015 We report that curcumin enhances the synthesis of DHA from its precursor, alpha-linolenic acid (C18:3 n-3; ALA) and elevates levels of enzymes involved in the synthesis of DHA such as FADS2 and elongase 2 in both liver and brain tissues. dehydroacetic acid 172-175 fatty acid desaturase 2 Homo sapiens 184-189