PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30400671-3 2018 Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) omega-3 polyunsaturated fatty acids may compete with AA for CYP450-dependent bioactive lipid mediator formation. Docosahexaenoic Acids 32-52 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 119-125 30400671-3 2018 Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) omega-3 polyunsaturated fatty acids may compete with AA for CYP450-dependent bioactive lipid mediator formation. Docosahexaenoic Acids 54-57 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 119-125 29080699-3 2018 CYP enzymes, previously identified as arachidonic acid (20:4n-6; AA) epoxygenases, accept eicosapentaenoic acid (20:5n-3; EPA) and docosahexaenoic acid (22:6n-3; DHA), the major fish oil n-3 LC-PUFAs, as efficient alternative substrates. Docosahexaenoic Acids 131-151 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-3 26975734-3 2016 In addition to arachidonic acid, the CYP epoxygenases also metabolize the Omega-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid and docosahexaenoic acid, to generate bioactive lipid epoxide mediators. Docosahexaenoic Acids 145-165 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 37-40 27182450-0 2015 CYP-epoxygenase metabolites of docosahexaenoic acid protect HL-1 cardiac cells against LPS-induced cytotoxicity Through SIRT1. Docosahexaenoic Acids 31-51 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-3 27182450-5 2015 Emerging evidence indicates that cytochrome P450 (CYP) epoxygenase metabolites of DHA, epoxydocosapentaenoic acids (EDPs), produce more potent biological activity compared to its precursor DHA. Docosahexaenoic Acids 82-85 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 33-48 27182450-5 2015 Emerging evidence indicates that cytochrome P450 (CYP) epoxygenase metabolites of DHA, epoxydocosapentaenoic acids (EDPs), produce more potent biological activity compared to its precursor DHA. Docosahexaenoic Acids 82-85 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 50-53 27182450-5 2015 Emerging evidence indicates that cytochrome P450 (CYP) epoxygenase metabolites of DHA, epoxydocosapentaenoic acids (EDPs), produce more potent biological activity compared to its precursor DHA. Docosahexaenoic Acids 189-192 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 33-48 27182450-5 2015 Emerging evidence indicates that cytochrome P450 (CYP) epoxygenase metabolites of DHA, epoxydocosapentaenoic acids (EDPs), produce more potent biological activity compared to its precursor DHA. Docosahexaenoic Acids 189-192 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 50-53 27182450-8 2015 Our results illustrate the CYP epoxygenase metabolite of DHA, 19,20-EDP, confers extensive protection to HL-1 cardiac cells against LPS-induced cytotoxicity via activation of SIRT1. Docosahexaenoic Acids 57-60 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 27-30 20869469-2 2011 As discussed in the present review, virtually all of the major AA metabolizing CYP isoforms accept a variety of other polyunsaturated fatty acids (PUFA), including linoleic, eicosapentaenoic (EPA) and docosahexaenoic acids (DHA), as efficient alternative substrates. Docosahexaenoic Acids 201-222 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 79-82 20869469-2 2011 As discussed in the present review, virtually all of the major AA metabolizing CYP isoforms accept a variety of other polyunsaturated fatty acids (PUFA), including linoleic, eicosapentaenoic (EPA) and docosahexaenoic acids (DHA), as efficient alternative substrates. Docosahexaenoic Acids 224-227 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 79-82