PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25169833-0 2014 C-2 selective arylation of indoles with heterogeneous nanopalladium and diaryliodonium salts. Indoles 27-34 complement C2 Homo sapiens 0-3 19507849-0 2009 Synthesis of tetrahydroisoquinocarbazoles via C-2 alkylation of indoles with 2-alkoxycyclopropanoate esters. Indoles 64-71 complement C2 Homo sapiens 46-49 23672506-3 2013 The new reaction mode features switching of the substituent from the indole C-3 position to the C-2 position (from the C-2 position to the C-3 position in the case of pyrrole) without loss of the enantiomeric purity, providing a novel concept in designing the asymmetric construction of enantiopure polycyclic indoles and pyrroles. Indoles 310-317 complement C2 Homo sapiens 96-99 23672506-3 2013 The new reaction mode features switching of the substituent from the indole C-3 position to the C-2 position (from the C-2 position to the C-3 position in the case of pyrrole) without loss of the enantiomeric purity, providing a novel concept in designing the asymmetric construction of enantiopure polycyclic indoles and pyrroles. Indoles 310-317 complement C2 Homo sapiens 119-122 24255969-4 2013 The resulting indoles can easily be transformed into diverse scaffolds, including 2,3- and 1,2-fused indoles, and indoles possessing an alpha,beta-unsaturated ketone moiety at the C-2 position. Indoles 14-21 complement C2 Homo sapiens 180-183 23076206-1 2012 Direct C-2 amidation of indoles was reported using sulfonyl azides as the amino source to release N(2) as the single byproduct. Indoles 24-31 complement C2 Homo sapiens 7-10 34582691-0 2021 Nickel-Catalyzed Dearomative Arylboration of Indoles: Regioselective Synthesis of C2- and C3-Borylated Indolines. Indoles 45-52 complement C2 Homo sapiens 82-92 17630734-0 2007 C-2/c-3 annulation and C-2 alkylation of indoles with 2-alkoxycyclopropanoate esters. Indoles 41-48 complement C2 Homo sapiens 0-7 17630734-0 2007 C-2/c-3 annulation and C-2 alkylation of indoles with 2-alkoxycyclopropanoate esters. Indoles 41-48 complement C2 Homo sapiens 0-3 15926829-0 2005 Direct palladium-catalyzed C-2 and C-3 arylation of indoles: a mechanistic rationale for regioselectivity. Indoles 52-59 complement C2 Homo sapiens 27-30 15926829-1 2005 We have recently developed palladium-catalyzed methods for direct arylation of indoles (and other azoles) wherein high C-2 selectivity was observed for both free (NH)-indole and (NR)-indole. Indoles 79-86 complement C2 Homo sapiens 119-122 12762681-3 2003 On the other hand, the N-amide 12, upon sequential or one-pot C-2 metalation, silylation, C-7 metalation, and electrophile treatment, furnishes indoles 7 in good overall yields. Indoles 144-151 complement C2 Homo sapiens 62-65 34553717-0 2021 Cp*Co(III)-catalyzed C2-thiolation and C2,C3-dithiolation of substituted indoles with N-(arylthio)succinimide. Indoles 73-80 complement C2 Homo sapiens 39-44 31282524-3 2019 As far as we know, this is the first report on the selective C-2 oxidation and C-3 monochlorination of simple indoles. Indoles 110-117 complement C2 Homo sapiens 61-64 31373493-0 2019 Mechanochemical Pd(II)-Catalyzed Direct and C-2-Selective Arylation of Indoles. Indoles 71-78 complement C2 Homo sapiens 44-47 31373493-2 2019 The developed protocol is highly C-2 selective and tolerant of structural variations with electron-rich and electron-deficient substituents both in indoles and iodoarenes. Indoles 148-155 complement C2 Homo sapiens 33-36 26176588-3 2015 Interestingly, C-2 alkynylation was also observed on C-3-substituted indoles, whereas classical C-3 alkynylation was obtained on selected unsubstituted indoles and 7-azaindole. Indoles 69-76 complement C2 Homo sapiens 15-18 31457739-3 2017 Highly selective C-2 functionalization of indoles was achieved in the presence of the highly reactive C-3 position. Indoles 42-49 complement C2 Homo sapiens 17-20 28102677-2 2017 The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit. Indoles 59-66 complement C2 Homo sapiens 76-79 28102677-2 2017 The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit. Indoles 59-66 complement C2 Homo sapiens 223-226 26247622-0 2015 Cu-mediated direct regioselective C-2 chlorination of indoles. Indoles 54-61 complement C2 Homo sapiens 34-37 26247622-1 2015 Cu-mediated C-2 chlorination of indoles was accomplished with copper(ii) chloride through the use of a directing pyrimidyl protection group. Indoles 32-39 complement C2 Homo sapiens 12-15 28745899-1 2017 The manganese-catalyzed addition of C-2 position of indoles to maleimides has been achieved under additive-free conditions. Indoles 52-59 complement C2 Homo sapiens 36-39 27878163-2 2016 It allows efficient and facile access to various C-2 cyanoalkylated furans, thiophenes, indoles, and pyrroles. Indoles 88-95 complement C2 Homo sapiens 49-52 27736082-0 2016 Electronic Nature of Ketone Directing Group as a Key To Control C-2 vs C-4 Alkenylation of Indoles. Indoles 91-98 complement C2 Homo sapiens 64-67 26923422-0 2016 Palladium-catalyzed regioselective C-2 arylation of 7-azaindoles, indoles, and pyrroles with arenes. Indoles 57-64 complement C2 Homo sapiens 35-38 26923422-1 2016 A palladium-catalyzed regioselective C-2 arylation of 7-azaindoles, indoles, and pyrroles with arenes has been developed. Indoles 59-66 complement C2 Homo sapiens 37-40 26263117-1 2015 A cobalt(III)-catalyzed C-2 selective C-H alkynylation of indoles using hypervalent iodine-alkyne reagents is described. Indoles 58-65 complement C2 Homo sapiens 24-27 26263117-2 2015 A broad range of synthetically useful functional groups (-F, -Cl, -Br, -CO2Me, -CN) were tolerated, providing an efficient and robust protocol for the synthesis of C-2 alkynylated indoles. Indoles 180-187 complement C2 Homo sapiens 164-167 25764265-1 2015 A new approach to C-2 arylated indoles has been developed by utilizing a ruthenium-catalyzed, heteroatom-directed regioselective C-H arylation. Indoles 31-38 complement C2 Homo sapiens 18-21