PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14666025-3 2003 This study was designed to compare the effects of epsilon-aminocaproic acid and aprotinin on plasma levels of interleukin-6 and interleukin-8 during and after cardiopulmonary bypass. Aminocaproic Acid 50-75 C-X-C motif chemokine ligand 8 Homo sapiens 128-141 14666025-7 2003 RESULTS: Both epsilon-aminocaproic acid and aprotinin administration resulted in significant (P <.05) reductions in D-dimer and interleukin-8 levels compared with saline. Aminocaproic Acid 14-39 C-X-C motif chemokine ligand 8 Homo sapiens 131-144 14666025-10 2003 CONCLUSIONS: When dosed in a similar manner, epsilon-aminocaproic acid seems to be as effective as aprotinin at reducing interleukin-6 and interleukin-8 levels in patients undergoing primary coronary artery bypass graft surgery. Aminocaproic Acid 45-70 C-X-C motif chemokine ligand 8 Homo sapiens 139-152