PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8445979-1	1993	Experiments were conducted on three different human liver samples to identify the cytochrome P450 isozyme which is involved in the biotransformation of the class III antiarrhythmic agent, amiodarone, into its major metabolite, desethylamiodarone (DEA).	desethylamiodarone	227-245	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	82-97	
27113703-2	2016	To investigate the role of drug metabolism in this liver toxicity, amiodarone and its major metabolite desethylamiodarone were incubated with HepG2 cells overexpressing a series of cytochrome P450 (CYP) isoforms.	desethylamiodarone	103-121	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	198-201	
8445979-1	1993	Experiments were conducted on three different human liver samples to identify the cytochrome P450 isozyme which is involved in the biotransformation of the class III antiarrhythmic agent, amiodarone, into its major metabolite, desethylamiodarone (DEA).	desethylamiodarone	247-250	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	82-97