PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9564625-2	1998	Long-term treatment with the MAO inhibitor tranylcypromine (1 mg/kg/day) resulted in sustained inhibition of MAO-A and MAO-B activities in liver and brain.	Tranylcypromine	43-58	monoamine oxidase B	Rattus norvegicus	119-124	
26955970-6	2016	The results show that (1) tranylcypromine (TCP), a known MAO inhibitor, increases sensitivity to the primary reinforcing effects of nicotine, shifting the dose-response curve for nicotine to the left, (2) inhibition of MAO-A, but not MAO-B, increases low-dose nicotine self-administration, (3) partial MAO-A inhibition, to the degree observed in chronic cigarette smokers, also increases low-dose nicotine self-administration, and (4) TCP decreases the threshold nicotine dose required for reinforcement enhancement.	Tranylcypromine	26-41	monoamine oxidase B	Rattus norvegicus	234-239	
26955970-6	2016	The results show that (1) tranylcypromine (TCP), a known MAO inhibitor, increases sensitivity to the primary reinforcing effects of nicotine, shifting the dose-response curve for nicotine to the left, (2) inhibition of MAO-A, but not MAO-B, increases low-dose nicotine self-administration, (3) partial MAO-A inhibition, to the degree observed in chronic cigarette smokers, also increases low-dose nicotine self-administration, and (4) TCP decreases the threshold nicotine dose required for reinforcement enhancement.	Tranylcypromine	43-46	monoamine oxidase B	Rattus norvegicus	234-239	
21414328-6	2011	Inhibition of both subtypes of monoamine oxidase (MAO-A and MAO-B) with tranylcypromine caused a reduction in both OS(ic) and OS(ec) whereas selective inhibition of MAO-A with clorgyline caused a reduction in Os(ic) but no change in OS(ec).	Tranylcypromine	72-87	monoamine oxidase B	Rattus norvegicus	60-65	
8749840-4	1995	Both TCP and (-)-deprenyl caused a greater reduction in the GABA-elevating action of PLZ than did clorgyline, suggesting that MAO-B is more important than MAO-A in the formation of the active metabolite of PLZ.	Tranylcypromine	5-8	monoamine oxidase B	Rattus norvegicus	126-131	
2587673-4	1989	In contrast to moclobemide, tranylcypromine is an irreversible and mixed MAO-A and MAO-B inhibitor with long-lasting effects.	Tranylcypromine	28-43	monoamine oxidase B	Rattus norvegicus	83-88	
7829993-2	1994	Normal rats treated with clorgyline (a selective MAO-A inhibitor) or tranylcypromine (a non-selective MAO inhibitor) showed a significantly diminished thyroid MAO activity, while deprenyl and pargyline (MAO-B inhibitors) did not modify the thyroidal enzyme activity with respect to the control group.	Tranylcypromine	69-84	monoamine oxidase B	Rattus norvegicus	203-208	
2248058-4	1990	Phenelzine, isocarboxazid and tranylcypromine were nonspecific, inhibiting MAO-A and MAO-B to about the same extent.	Tranylcypromine	30-45	monoamine oxidase B	Rattus norvegicus	85-90	
3508523-6	1987	Both CE-TCP and TCP inhibited MAO-A and MAO-B, with maximum inhibition occurring 60 min after CE-TCP dosing and 30 min after dosing with TCP, times at which brain concentrations of CE-TCP and TCP were at the maximum.	Tranylcypromine	8-11	monoamine oxidase B	Rattus norvegicus	40-45	
3508523-6	1987	Both CE-TCP and TCP inhibited MAO-A and MAO-B, with maximum inhibition occurring 60 min after CE-TCP dosing and 30 min after dosing with TCP, times at which brain concentrations of CE-TCP and TCP were at the maximum.	Tranylcypromine	16-19	monoamine oxidase B	Rattus norvegicus	40-45	
3508523-6	1987	Both CE-TCP and TCP inhibited MAO-A and MAO-B, with maximum inhibition occurring 60 min after CE-TCP dosing and 30 min after dosing with TCP, times at which brain concentrations of CE-TCP and TCP were at the maximum.	Tranylcypromine	16-19	monoamine oxidase B	Rattus norvegicus	40-45