PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21864674-2	2012	SHIP1 mediates its regulatory function after relocalization from the cytoplasm to the plasma membrane where it converts its substrate PI(3,4,5)P(3) to PI(3,4)P(2) thereby terminating PI3-kinase mediated signaling.	pi(3,4)p	151-159	inositol polyphosphate-5-phosphatase D	Homo sapiens	0-5	
22876243-4	2012	One such target is the SH2 domain-containing inositol-5-phosphatase-1 (SHIP-1) which de-phosphorylates PI(3,4,5)P(3) at the D5 position of the inositol ring to create PI(3,4)P(2).	pi(3,4)p	167-175	inositol polyphosphate-5-phosphatase D	Homo sapiens	23-69	
22876243-4	2012	One such target is the SH2 domain-containing inositol-5-phosphatase-1 (SHIP-1) which de-phosphorylates PI(3,4,5)P(3) at the D5 position of the inositol ring to create PI(3,4)P(2).	pi(3,4)p	167-175	inositol polyphosphate-5-phosphatase D	Homo sapiens	71-77	
21155837-3	2011	This review also proposes that SHIP can have either inhibitory or activating roles in cell signaling that are determined by whether signaling pathways distal to PI3K are promoted by SHIP"s substrate (PI(3,4,5)P(3) ) or its product (PI(3,4)P(2) ).	pi(3,4)p	232-240	inositol polyphosphate-5-phosphatase D	Homo sapiens	31-35	
21155837-3	2011	This review also proposes that SHIP can have either inhibitory or activating roles in cell signaling that are determined by whether signaling pathways distal to PI3K are promoted by SHIP"s substrate (PI(3,4,5)P(3) ) or its product (PI(3,4)P(2) ).	pi(3,4)p	232-240	inositol polyphosphate-5-phosphatase D	Homo sapiens	182-186	
19782768-4	2010	One level of control involves the Src homology 2 domain-containing inositol-5-phosphatase-1 (SHIP-1) that modulates phosphoinositide 3-kinase signaling by degrading the key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2), but also serves as a key scaffolding molecule in the formation of multi-protein complexes.	pi(3,4)p	206-214	inositol polyphosphate-5-phosphatase D	Homo sapiens	34-91	
19782768-4	2010	One level of control involves the Src homology 2 domain-containing inositol-5-phosphatase-1 (SHIP-1) that modulates phosphoinositide 3-kinase signaling by degrading the key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2), but also serves as a key scaffolding molecule in the formation of multi-protein complexes.	pi(3,4)p	206-214	inositol polyphosphate-5-phosphatase D	Homo sapiens	93-99