PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31737841-0 2019 Photoexcited Toluidine Blue Inhibits Tau Aggregation in Alzheimer"s Disease. Tolonium Chloride 13-27 tau Drosophila melanogaster 37-40 31737841-7 2019 Biochemical and biophysical analyses using sodium dodecyl sulfate-polyacrylamide gel electrophoresis, ThS fluorescence, circular dichroism spectroscopy, and electron microscopy suggested that toluidine blue inhibited the aggregation of Tau in vitro. Tolonium Chloride 192-206 tau Drosophila melanogaster 236-239 31737841-8 2019 The photoexcited toluidine blue potentially dissolved the matured Tau fibrils, which indicated the disaggregation property of toluidine blue. Tolonium Chloride 17-31 tau Drosophila melanogaster 66-69 31737841-8 2019 The photoexcited toluidine blue potentially dissolved the matured Tau fibrils, which indicated the disaggregation property of toluidine blue. Tolonium Chloride 126-140 tau Drosophila melanogaster 66-69 31737841-11 2019 The studies in a UAS Tau E14 transgenic Drosophila model suggested that photoexcited toluidine blue was potent to restore the survival and memory deficits of Drosophila. Tolonium Chloride 85-99 tau Drosophila melanogaster 21-24 31737841-12 2019 The overall finding of our studies suggested toluidine blue to be a potent molecule in rescuing the Tau-mediated pathology by inhibiting its aggregation, reducing the cell death, and modulating the tubulin levels and behavioral characteristics of Drosophila. Tolonium Chloride 45-59 tau Drosophila melanogaster 100-103