PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19741095-8 2009 Our results demonstrate that the PI(4,5)P(2) regulatory mechanism, that is governed by EGF-dependent phospholipase C activation, is a determinant for the spatial and temporal control of cofilin activation required for lamellipodia initiation. pi(4,5)p(2) 33-44 cofilin 1 Homo sapiens 186-193 22907655-11 2012 Our data suggest that PI(4,5)P(2) dephosphorylation through OCRL regulates a Rac1-cofilin signalling cascade implicated in MPR trafficking from endosomes to the TGN. pi(4,5)p(2) 22-33 cofilin 1 Homo sapiens 82-89 20483342-5 2010 Our analysis revealed that cofilin does not harbor a specific PI(4,5)P(2)-binding pocket, but instead interacts with PI(4,5)P(2) through a large, positively charged surface of the molecule. pi(4,5)p(2) 62-73 cofilin 1 Homo sapiens 27-34