PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23262302-5	2013	Bis-Mep was found to be a mixed-type inhibitor on electric eel AChE by enzyme kinetic study.	bis(9)-normeptazinol	0-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	63-67	
23262302-6	2013	Molecular docking revealed that two "water bridges" located at the two wings of Bis-Mep stabilized its interaction with both catalytic and peripheral anionic sites of AChE.	bis(9)-normeptazinol	80-87	acetylcholinesterase (Cartwright blood group)	Homo sapiens	167-171	
23262302-8	2013	The maximal cognitive amelioration of Bis-Mep was achieved at 100 ng/kg, comparable with the effect of a reference drug Huperzine A at 1 mg/kg and also the relevant AChE inhibition in brain.	bis(9)-normeptazinol	38-45	acetylcholinesterase (Cartwright blood group)	Homo sapiens	165-169	
23262302-9	2013	These findings suggested that Bis-Mep might be a promising dual-binding AChE inhibitor for potential AD therapeutics.	bis(9)-normeptazinol	30-37	acetylcholinesterase (Cartwright blood group)	Homo sapiens	72-76