PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30371861-6 2019 Functional CYP polymorphisms can significantly alter opiate levels resulting in inadequate analgesia or life-threatening toxicity. Opiate Alkaloids 53-59 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 11-14 21603375-11 2010 One of the newer opiates, oxymorphone, has recently been studied as it is metabolized in a non-cytochrome P-450 pathway and therefore bypasses many of the drug-drug interactions common to the elderly. Opiate Alkaloids 17-24 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 95-111