PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11507101-0	2001	Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.	Leukotriene C4	31-45	ATP binding cassette subfamily B member 1	Homo sapiens	55-85	
11306701-1	2001	The 190-kDa phosphoglycoprotein multidrug resistance protein 1 (MRP1) (ABCC1) confers resistance to a broad spectrum of anticancer drugs and also actively transports certain xenobiotics with reduced glutathione (GSH) (cotransport) as well as conjugated organic anions such as leukotriene C(4) (LTC(4)).	Leukotriene C4	276-289	ATP binding cassette subfamily B member 1	Homo sapiens	32-62	
11306701-1	2001	The 190-kDa phosphoglycoprotein multidrug resistance protein 1 (MRP1) (ABCC1) confers resistance to a broad spectrum of anticancer drugs and also actively transports certain xenobiotics with reduced glutathione (GSH) (cotransport) as well as conjugated organic anions such as leukotriene C(4) (LTC(4)).	Leukotriene C4	276-289	ATP binding cassette subfamily B member 1	Homo sapiens	64-68	
11278596-5	2001	This mutation created a protein that conferred resistance to doxorubicin without affecting vincristine resistance, or the ability of mrp1 to transport leukotriene C(4) (LTC(4)) and 17beta-estradiol 17-(beta-d-glucuronide) (E(2)17betaG).	Leukotriene C4	151-164	ATP binding cassette subfamily B member 1	Homo sapiens	133-137	
11102445-9	2001	We found that estradiol and estrone 3-sulfate alone were poor competitors of MRP1-mediated transport of the cysteinyl leukotriene, leukotriene C(4).	Leukotriene C4	131-144	ATP binding cassette subfamily B member 1	Homo sapiens	77-81	
12731862-3	2003	MRP1 also transports GSSG and GSH as well as conjugated organic anions, including leukotriene C(4) and 17beta-estradiol 17-(beta-D-glucuronide) and certain xenobiotics in association with GSH.	Leukotriene C4	82-95	ATP binding cassette subfamily B member 1	Homo sapiens	0-4	
16105987-0	2005	Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites.	Leukotriene C4	163-177	ATP binding cassette subfamily B member 1	Homo sapiens	18-48	
15628876-0	2005	The leucotriene C4 binding sites in multidrug resistance protein 1 (ABCC1) include the first membrane multiple spanning domain.	Leukotriene C4	4-18	ATP binding cassette subfamily B member 1	Homo sapiens	36-66	
11721885-7	2001	Transport of the MRP1 substrates leukotriene C4, 17beta-estradiol 17beta-(D)-glucuronide, and estrone sulfate by membrane vesicles prepared from transiently transfected HEKSV293T cells was comparable to that of wild-type MRP1.	Leukotriene C4	33-47	ATP binding cassette subfamily B member 1	Homo sapiens	17-21	
10385244-2	1999	The intracellular transport of leukotriene C4 (LTC4) in hematopoietic cells such as human monocytes is controlled by an ATP dependent carrier encoded by the multidrug resistance protein1 (MRPI) gene whose function can be blocked by the compound MK-571.	Leukotriene C4	31-45	ATP binding cassette subfamily B member 1	Homo sapiens	157-186	
10385244-2	1999	The intracellular transport of leukotriene C4 (LTC4) in hematopoietic cells such as human monocytes is controlled by an ATP dependent carrier encoded by the multidrug resistance protein1 (MRPI) gene whose function can be blocked by the compound MK-571.	Leukotriene C4	31-45	ATP binding cassette subfamily B member 1	Homo sapiens	188-192	
31268744-0	2019	Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1).	Leukotriene C4	32-46	ATP binding cassette subfamily B member 1	Homo sapiens	69-99	
31268744-0	2019	Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1).	Leukotriene C4	32-46	ATP binding cassette subfamily B member 1	Homo sapiens	101-105	
31268744-1	2019	The human multidrug resistance protein 1 (hMRP1) transporter is implicated in cancer multidrug resistance as well as immune responses involving its physiologic substrate, glutathione (GSH)-conjugated leukotriene C4 (LTC4).	Leukotriene C4	200-214	ATP binding cassette subfamily B member 1	Homo sapiens	10-40	
19398503-8	2009	Finally, the differing abilities of the cysteinyl leukotriene derivatives leukotriene C(4), D(4), and F(4) to inhibit estradiol glucuronide transport by wild-type and K332L mutant MRP1 provide further evidence that TM6-Lys(332) is involved in the recognition of the gamma-Glu portion of substrates and modulators containing GSH or GSH-like moieties.	Leukotriene C4	74-87	ATP binding cassette subfamily B member 1	Homo sapiens	180-184	
16481346-1	2006	Multidrug resistance protein-1 (MRP1) belongs to subfamily C of the ATP-binding cassette transporters, and exports leukotriene C(4) and organic anions including the fluorescent calcium indicator indo-1.	Leukotriene C4	115-128	ATP binding cassette subfamily B member 1	Homo sapiens	0-30	
16481346-1	2006	Multidrug resistance protein-1 (MRP1) belongs to subfamily C of the ATP-binding cassette transporters, and exports leukotriene C(4) and organic anions including the fluorescent calcium indicator indo-1.	Leukotriene C4	115-128	ATP binding cassette subfamily B member 1	Homo sapiens	32-36