PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2510565-0 1989 Identification of an alveolar macrophage-derived activity in bronchial asthma that enhances leukotriene C4 generation by human eosinophils stimulated by ionophore A23187 as a granulocyte-macrophage colony-stimulating factor. Leukotriene C4 92-106 colony stimulating factor 2 Homo sapiens 175-223 12097406-10 2002 Immobilized lactoferrin also stimulated release of eosinophil-derived neurotoxin and low levels of leukotriene C4 production; the latter was significantly enhanced in the presence of 100 pg/ml GM-CSF. Leukotriene C4 99-113 colony stimulating factor 2 Homo sapiens 193-199 1645746-0 1991 Eosinophils altered phenotypically and primed by culture with granulocyte/macrophage colony-stimulating factor and 3T3 fibroblasts generate leukotriene C4 in response to FMLP. Leukotriene C4 140-154 colony stimulating factor 2 Homo sapiens 62-110 19856299-1 1997 This study demonstrates the changing levels of leukotrieneB4 (LTB4) and leukotrieneC4 (LTC4) generated by human white blood cells primed with different human interleukins IL-3, IL-5, IL-6, IL-8 and with human hematopoietic growth factor granulocyte-macrophage colony stimulating factor (GM-CSF). Leukotriene C4 72-85 colony stimulating factor 2 Homo sapiens 287-293 1550768-4 1992 GM-CSF and IL-3 enhanced the generation of leukotriene C4 (LTC4) induced by calcium ionophore A23187 and the release of arylsulphatase and beta-glucuronidase from specific and small granules of eosinophils. Leukotriene C4 43-57 colony stimulating factor 2 Homo sapiens 0-6 1533539-4 1992 In a basophil mediator release assay, three peptides inhibited the priming effect of interleukin (IL)-3, IL-5, and granulocyte/macrophage colony-stimulating factor (GM-CSF) on synthesis of leukotriene C4 induced by chemotactic peptides. Leukotriene C4 189-203 colony stimulating factor 2 Homo sapiens 115-163 1533539-4 1992 In a basophil mediator release assay, three peptides inhibited the priming effect of interleukin (IL)-3, IL-5, and granulocyte/macrophage colony-stimulating factor (GM-CSF) on synthesis of leukotriene C4 induced by chemotactic peptides. Leukotriene C4 189-203 colony stimulating factor 2 Homo sapiens 165-171 3120489-7 1987 Moreover, cisternal CSF level of prostaglandin D2 and leukotriene C4 are significantly higher in patients with symptomatic vasospasm. Leukotriene C4 54-68 colony stimulating factor 2 Homo sapiens 20-23 3095427-2 1986 Here we show that purified biosynthetic (recombinant) human T lymphocyte granulocyte-macrophage colony-stimulating factor (GM-CSF) enhanced markedly two eosinophil functions: cytotoxicity toward schistosomula by a mean of 676%, and calcium ionophore A23187-induced generation of leukotriene C4 (LTC4) by a mean of 135%. Leukotriene C4 279-293 colony stimulating factor 2 Homo sapiens 73-121 3095427-2 1986 Here we show that purified biosynthetic (recombinant) human T lymphocyte granulocyte-macrophage colony-stimulating factor (GM-CSF) enhanced markedly two eosinophil functions: cytotoxicity toward schistosomula by a mean of 676%, and calcium ionophore A23187-induced generation of leukotriene C4 (LTC4) by a mean of 135%. Leukotriene C4 279-293 colony stimulating factor 2 Homo sapiens 123-129