PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21106245-3 2011 The release of beta-hexosaminidase, leukotriene C(4), and IL-8, but not IL-6, was strongly enhanced in response to sequential challenge of mast cells with IL-4, SCF and FceRI cross-linking compared to stimulation by FceRI cross-linking alone. Leukotriene C4 36-49 interleukin 4 Homo sapiens 155-159 15962102-4 2005 Stimulation for release of specific cytokines, such as IL-4, leads to a regulated signal transduction cascade, which is dependent on the formation of leukotriene C4 within eosinophils where it acts as an intracrine mediator. Leukotriene C4 150-164 interleukin 4 Homo sapiens 55-59 12797482-10 2003 Endothelial cell pretreatment with IL-4 or IL-1beta further increased leukotriene C4 release (1,789.1 and 2,895.1 pg x mL(-1), respectively), whereas pretreatment with IFN-gamma decreased it (293.7 pg x mL(-1)). Leukotriene C4 70-84 interleukin 4 Homo sapiens 35-39 9130503-6 1997 Studies about the regulation of IgE-dependent and -independent IL-4/IL-13 expression by different cytokines, growth factors and chemokines demonstrate that the different basophil effector functions such as chemotaxis, exocytosis, leukotriene C4 formation and cytokine expression are regulated separately. Leukotriene C4 230-244 interleukin 4 Homo sapiens 63-67 10393951-5 1999 Moreover, IL-4, which by itself had no visible effect on human MC, enhanced the release of histamine, leukotriene C4, and IL-5 in MC triggered by IgE receptor crosslinking. Leukotriene C4 102-116 interleukin 4 Homo sapiens 10-14 31783259-2 2020 A number of activators including interleukin 3 (IL-3) and IgE have been identified in the regulation of human basophils expressing mediators such as histamine and leukotriene C4 (LTC4) and cytokines, including IL-4 and IL-13. Leukotriene C4 179-183 interleukin 4 Homo sapiens 210-214