PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26221052-4 2015 Orai1 is also a pore-forming subunit of an arachidonic acid (or leukotriene C4)-regulated current Iarc that involves interactions among Orai1, Orai3, and STIM1. Leukotriene C4 64-78 ORAI calcium release-activated calcium modulator 1 Homo sapiens 0-5 32659517-7 2020 Further, mammalian specific homolog Orai3 forms heteromultimeric channel with Orai1 for constituting Arachidonic acid regulated Ca2+ (ARC) channels or arachidonic acid metabolite Leukotriene C4 (LTC4) regulated Ca2+ (LRC) channels. Leukotriene C4 179-193 ORAI calcium release-activated calcium modulator 1 Homo sapiens 78-83 26221052-4 2015 Orai1 is also a pore-forming subunit of an arachidonic acid (or leukotriene C4)-regulated current Iarc that involves interactions among Orai1, Orai3, and STIM1. Leukotriene C4 64-78 ORAI calcium release-activated calcium modulator 1 Homo sapiens 136-141 23515871-2 2013 Furthermore, STIM1 and Orai1, along with Orai3, encode store-independent Ca(2+) currents regulated by either arachidonate or its metabolite, leukotriene C4. Leukotriene C4 141-155 ORAI calcium release-activated calcium modulator 1 Homo sapiens 23-28 23878392-3 2013 These store-independent Orai3/Orai1 channels are gated by cytosolic leukotriene C4 (LTC4) and require STIM1 downstream LTC4 action. Leukotriene C4 68-82 ORAI calcium release-activated calcium modulator 1 Homo sapiens 30-35 23349245-7 2013 Rather, the signal for Orai1/3 channel activation is cytosolic leukotrieneC4 produced downstream thrombin receptor stimulation through the catalytic activity of leukotrieneC4 synthase. Leukotriene C4 63-76 ORAI calcium release-activated calcium modulator 1 Homo sapiens 23-30