PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27438-5 1978 The determination of the CSF/blood relationship of individual parameters shows a significant increase of the lactate quotient as well as a decrease of the pH quotient and of bicarbonate quotient. Bicarbonates 174-185 colony stimulating factor 2 Homo sapiens 25-28 8092567-8 1994 During respiratory acidosis, [HCO3-] increases in extracellular fluids to control cerebral pH by two main ways: a carbonic anhydrase activation at the blood/brain and blood/CSF barriers level and an increase in chloride shift in glial cells (HCO3- exchanged for Cl-). Bicarbonates 30-34 colony stimulating factor 2 Homo sapiens 173-176 2154185-9 1990 These effects of GM-CSF and PAF on Na+/H+ exchange are observed in both bicarbonate-free and bicarbonate-containing medium. Bicarbonates 72-83 colony stimulating factor 2 Homo sapiens 17-23 2154185-9 1990 These effects of GM-CSF and PAF on Na+/H+ exchange are observed in both bicarbonate-free and bicarbonate-containing medium. Bicarbonates 93-104 colony stimulating factor 2 Homo sapiens 17-23 3129145-0 1988 Regulation of pH and HCO3 in brain and CSF of the developing mammalian central nervous system. Bicarbonates 21-25 colony stimulating factor 2 Homo sapiens 39-42 3129145-6 1988 Throughout postnatal ontogenesis, [HCO3]csf was more resistant to alteration by metabolic acidosis than by alkalosis. Bicarbonates 35-39 colony stimulating factor 2 Homo sapiens 40-43 7375186-1 1980 We evaluated CSF [HCO3-] regulation in lightly anesthetized newborn puppies following: (1) acute total asphyxia; (2) metabolic acidosis; and (3) metabolic acidosis induced after acute asphyxia. Bicarbonates 18-22 colony stimulating factor 2 Homo sapiens 13-16 7375186-2 1980 Five and one-half min of total asphyxia resulted in a 4.4 mM/liter decrease in mean CSF [HCO3-]. Bicarbonates 89-93 colony stimulating factor 2 Homo sapiens 84-87 7375186-3 1980 During 65 min of recovery with mechanical ventilation mean CSF [HCO3-] increased 1.7 mM/liter. Bicarbonates 64-68 colony stimulating factor 2 Homo sapiens 59-62 7375186-6 1980 With acidosis in nonasphyxiated control puppies, CSF [HCO3-] decreased steadily. Bicarbonates 54-59 colony stimulating factor 2 Homo sapiens 49-52 7375186-7 1980 At 4 hr, the ratio, delta CSF [HCO3-]/delta plasma [HCO3-], was 0.43, a value close to that observed in adults of many species with metabolic acid-base disturbances, 0.41. Bicarbonates 31-35 colony stimulating factor 2 Homo sapiens 26-29 7375186-8 1980 With acidosis in asphyxiated puppies allowed 1 hr of recovery, the time course and mean values of plasma and CSF [HCO3-] were indistinguishable from those of the nonasphyxiated acidotic controls. Bicarbonates 114-118 colony stimulating factor 2 Homo sapiens 109-112 7375186-9 1980 Newborn puppies appear to regulate CSF [HCO3-] in response to acute asphyxia or metabolic acidosis, and acute asphyxia does not impair the puppy"s ability to regulate CSF [HCO3-] in metabolic acidosis. Bicarbonates 40-44 colony stimulating factor 2 Homo sapiens 35-38 29457-0 1978 Interaction between PCO2 and plasma [HCO-3] in regulation of CSF [HCO-3] in respiratory alkalosis and metabolic acidosis. Bicarbonates 37-42 colony stimulating factor 2 Homo sapiens 61-64 632156-0 1978 Regulation of CSF[HCO3-] during long-term hypoxic hypocapnia in man. Bicarbonates 18-22 colony stimulating factor 2 Homo sapiens 14-17 29457-0 1978 Interaction between PCO2 and plasma [HCO-3] in regulation of CSF [HCO-3] in respiratory alkalosis and metabolic acidosis. Bicarbonates 66-71 colony stimulating factor 2 Homo sapiens 61-64 5575413-0 1971 The CDF-blood potential and the regulation of the bicarbonate concentration of CSF during acidosis in the cat. Bicarbonates 50-61 colony stimulating factor 2 Homo sapiens 79-82 5765-0 1976 Dependence of CSF on plasma bicarbonate during hypocapnia and hypoxemic hypocapnia. Bicarbonates 28-39 colony stimulating factor 2 Homo sapiens 14-17 5765-1 1976 We have previoulsy shown pH compensation to be similar in CSF and arterial blood during chronic hypoxemic hypocapnia in man and pony, and postulated that the compensatory reduction in CSF [HCO3] was dependent upon corresponding changes in [HCO3]a. Bicarbonates 189-193 colony stimulating factor 2 Homo sapiens 184-187 5765-1 1976 We have previoulsy shown pH compensation to be similar in CSF and arterial blood during chronic hypoxemic hypocapnia in man and pony, and postulated that the compensatory reduction in CSF [HCO3] was dependent upon corresponding changes in [HCO3]a. Bicarbonates 240-244 colony stimulating factor 2 Homo sapiens 184-187 5765-4 1976 In hypocapnia and hypoxemic hypocapnia, the decrease in [HCO3] and % pH compensation in CSF were less than or equal to that in arterial blood. Bicarbonates 57-61 colony stimulating factor 2 Homo sapiens 88-91 5765-5 1976 Most (51-89%) of the compensatory decrease in CSF [HCO3] was prevented by preventing the corresponding reduction in [HCO3]a. Bicarbonates 51-55 colony stimulating factor 2 Homo sapiens 46-49 5765-5 1976 Most (51-89%) of the compensatory decrease in CSF [HCO3] was prevented by preventing the corresponding reduction in [HCO3]a. Bicarbonates 117-121 colony stimulating factor 2 Homo sapiens 46-49 5765-6 1976 This dependence of changes in CSF on plasma [HCO3] required a concurrent decrease in CSF PCO2, but was largely independent of variations in plasma pH. Bicarbonates 45-49 colony stimulating factor 2 Homo sapiens 30-33 5765-6 1976 This dependence of changes in CSF on plasma [HCO3] required a concurrent decrease in CSF PCO2, but was largely independent of variations in plasma pH. Bicarbonates 45-49 colony stimulating factor 2 Homo sapiens 85-88 5765-7 1976 A minor but significant portion of the decrease in CSF [HCO3] was achieved independently of corresponding changes in [HCO3]a. Bicarbonates 56-60 colony stimulating factor 2 Homo sapiens 51-54 5765-7 1976 A minor but significant portion of the decrease in CSF [HCO3] was achieved independently of corresponding changes in [HCO3]a. Bicarbonates 118-122 colony stimulating factor 2 Homo sapiens 51-54 5765-8 1976 The contribution of this local mechanism to CSF [HCO3] regulation increased with increasing severity of hypocapnia or hypoxemia and was usually associated with a selective increase in CSF lactate. Bicarbonates 49-53 colony stimulating factor 2 Homo sapiens 44-47 5765-8 1976 The contribution of this local mechanism to CSF [HCO3] regulation increased with increasing severity of hypocapnia or hypoxemia and was usually associated with a selective increase in CSF lactate. Bicarbonates 49-53 colony stimulating factor 2 Homo sapiens 184-187 5765-9 1976 It was concluded that [HCO3] regulation in the CSF during hypoxemic hypocapnia was primarily dependent upon, and therefore limited by, the concomitant decrease in plasma [HCO3]. Bicarbonates 23-27 colony stimulating factor 2 Homo sapiens 47-50 5765-9 1976 It was concluded that [HCO3] regulation in the CSF during hypoxemic hypocapnia was primarily dependent upon, and therefore limited by, the concomitant decrease in plasma [HCO3]. Bicarbonates 171-175 colony stimulating factor 2 Homo sapiens 47-50 4102771-0 1971 The CSF-blood potential and the adaptation of the CSF bicarbonate concentration in the cat. Bicarbonates 54-65 colony stimulating factor 2 Homo sapiens 50-53 65979-0 1976 Mechanisms of CSF bicarbonate formation in normocapnia. Bicarbonates 18-29 colony stimulating factor 2 Homo sapiens 14-17 64158-0 1976 CSF bicarbonate regulation in hypercapnia and its relationship to brain ammonia and amino acids. Bicarbonates 4-15 colony stimulating factor 2 Homo sapiens 0-3 5552796-0 1971 The effect of iso-carbic metabolic acidosis in blood on [H+] and [HCO3-] in CSF with deductions about the regulation of an active transport of H plus-HCO3-between blood and CSF. Bicarbonates 66-70 colony stimulating factor 2 Homo sapiens 76-79 5552796-0 1971 The effect of iso-carbic metabolic acidosis in blood on [H+] and [HCO3-] in CSF with deductions about the regulation of an active transport of H plus-HCO3-between blood and CSF. Bicarbonates 66-70 colony stimulating factor 2 Homo sapiens 173-176 5552796-0 1971 The effect of iso-carbic metabolic acidosis in blood on [H+] and [HCO3-] in CSF with deductions about the regulation of an active transport of H plus-HCO3-between blood and CSF. Bicarbonates 150-154 colony stimulating factor 2 Homo sapiens 76-79 5552796-0 1971 The effect of iso-carbic metabolic acidosis in blood on [H+] and [HCO3-] in CSF with deductions about the regulation of an active transport of H plus-HCO3-between blood and CSF. Bicarbonates 150-154 colony stimulating factor 2 Homo sapiens 173-176 5901159-7 1966 The metabolic acidosis which results is likely the basis of the respiratory stimulatin, perhaps by its effects on the CSF H(2)CO(3)-HCO(3) - system. Bicarbonates 132-138 colony stimulating factor 2 Homo sapiens 118-121 21082368-7 2011 CSF formation occurs by basolateral carrier-mediated uptake of Na+, Cl-, and HCO3-, followed by apical release via ion channel conductance and osmotic flow of water through AQP1 channels. Bicarbonates 77-81 colony stimulating factor 2 Homo sapiens 0-3 17883837-7 2007 Both have significant HCO3- permeability, and may play a role in CSF secretion. Bicarbonates 22-26 colony stimulating factor 2 Homo sapiens 65-68