PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24694986-6	2014	By contrast, urine excretion of angiotensinogen, an index of kidney angiotensin II, increased in Usual Care but decreased with bicarbonate or fruits and vegetables.	Bicarbonates	127-138	angiotensinogen	Homo sapiens	32-47	
25527741-11	2015	CONCLUSIONS: AII-mediated GFR decline in 2/3 Nx was induced by H(+) retention and its amelioration with dietary HCO3 conserved GFR better than AII receptor antagonism in this CKD model.	Bicarbonates	112-116	angiotensinogen	Homo sapiens	13-16	
2172615-4	1990	Angiotensin II also appears to regulate bicarbonate transport, especially in the S1 segment.	Bicarbonates	40-51	angiotensinogen	Homo sapiens	0-14	
24694986-0	2014	Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate.	Bicarbonates	115-126	angiotensinogen	Homo sapiens	141-156	
19861352-6	2010	For example, mucosaprotective duodenal bicarbonate-rich secretion is inhibited by Ang II via type 1 (AT(1)) receptor-mediated facilitation of sympathoadrenergic activity, but this secretory process can also be stimulated by Ang II via AT(2) receptors.	Bicarbonates	39-50	angiotensinogen	Homo sapiens	82-88	
19861352-6	2010	For example, mucosaprotective duodenal bicarbonate-rich secretion is inhibited by Ang II via type 1 (AT(1)) receptor-mediated facilitation of sympathoadrenergic activity, but this secretory process can also be stimulated by Ang II via AT(2) receptors.	Bicarbonates	39-50	angiotensinogen	Homo sapiens	224-230	
16142301-2	2005	In addition, angiotensin II stimulates H+ secretion and HCO3- reabsorption in both proximal and distal tubules and regulates H+-ATPase activity in intercalated cells of the collecting tubule.	Bicarbonates	56-60	angiotensinogen	Homo sapiens	13-27	
16204762-5	2005	Although losartan alone did not affect the HCO3- secretion, despite reducing MBP, the agent dose-dependently increased the HCO3- secretion in the presence of angiotensin II, and this response was totally antagonized by prior administration of FR172357, indomethacin and L-NAME.	Bicarbonates	123-127	angiotensinogen	Homo sapiens	158-172	
16204762-8	2005	These results suggest that both an ACE inhibitor and AT1 antagonist (in the presence of angiotensin II) increase duodenal HCO3- secretion via a common pathway, involving bradykinin, NO and PGs.	Bicarbonates	122-126	angiotensinogen	Homo sapiens	88-102	
16142301-3	2005	Different results regarding the effect of angiotensin II on bicarbonate reabsorption and proton secretion have been reported at the functional level, depending on the angiotensin II concentration and tubule segment studied.	Bicarbonates	60-71	angiotensinogen	Homo sapiens	42-56	
15990874-6	2005	Angiotensin II (AngII), which activates PKC, decreased Cl-/HCO3- exchange in cells coexpressing SLC26A6 and AT1a-AngII receptor.	Bicarbonates	59-63	angiotensinogen	Homo sapiens	0-14	
15990874-6	2005	Angiotensin II (AngII), which activates PKC, decreased Cl-/HCO3- exchange in cells coexpressing SLC26A6 and AT1a-AngII receptor.	Bicarbonates	59-63	angiotensinogen	Homo sapiens	16-21	
15990874-6	2005	Angiotensin II (AngII), which activates PKC, decreased Cl-/HCO3- exchange in cells coexpressing SLC26A6 and AT1a-AngII receptor.	Bicarbonates	59-63	angiotensinogen	Homo sapiens	113-118	
9892162-5	1999	Although the mechanisms responsible for the regulation of intratubular AngII concentrations remain to be determined, micropuncture studies have provided direct evidence that activation of intraluminal AT1 receptors by AngII exerts a substantial stimulatory influence on sodium and bicarbonate transport by both proximal and distal tubules.	Bicarbonates	281-292	angiotensinogen	Homo sapiens	218-223	
11739292-0	2001	Molecular basis for angiotensin II-induced increase of chloride/bicarbonate exchange in the myocardium.	Bicarbonates	64-75	angiotensinogen	Homo sapiens	20-34	
8945991-3	1996	In the presence of angiotensin II (ANG II) (10(-12) M), a significant increase in HCO3- reabsorption was observed both in ED (from 0.930 +/- 0.060 to 2.64 +/- 0.210 nmol.cm-2.s-1 in luminally perfused tubules and from 0.850 +/- 0.040 to 2.03 +/- 0.210 nmol.cm-2.s-1 during capillary perfusion) and LD segments from 0.310 +/- 0.130 to 2.16 +/- 0.151 nmol.cm-2.s-1 during luminal perfusion and from 0.530 +/- 0.031 to 2.16 +/- 0.211 nmol.cm-2.s-1 with capillary perfusion).	Bicarbonates	82-86	angiotensinogen	Homo sapiens	19-33	
9530271-9	1998	The magnitude of the stimulated response to angiotensin II by Na/H and Na-dependent Cl/HCO3 exchanger in adult and tMCs is unchanged throughout development.	Bicarbonates	87-91	angiotensinogen	Homo sapiens	44-58	
8945991-3	1996	In the presence of angiotensin II (ANG II) (10(-12) M), a significant increase in HCO3- reabsorption was observed both in ED (from 0.930 +/- 0.060 to 2.64 +/- 0.210 nmol.cm-2.s-1 in luminally perfused tubules and from 0.850 +/- 0.040 to 2.03 +/- 0.210 nmol.cm-2.s-1 during capillary perfusion) and LD segments from 0.310 +/- 0.130 to 2.16 +/- 0.151 nmol.cm-2.s-1 during luminal perfusion and from 0.530 +/- 0.031 to 2.16 +/- 0.211 nmol.cm-2.s-1 with capillary perfusion).	Bicarbonates	82-86	angiotensinogen	Homo sapiens	35-41	
8230088-7	1993	Intravascular angiotensin II receptors are implicated in the central release of vasopressin and other hypophyseal hormones, in increasing sympathetic outflow, in the thirst response and, possibly, in cognitive function; in the inotropic and chronotropic effects of angiotensin II on the heart as well as in growth/hypertrophy; in the control of aldosterone release and in the balance between cortisol and aldosterone secretion; and in modulating sodium, chloride and bicarbonate transport within the kidney.	Bicarbonates	467-478	angiotensinogen	Homo sapiens	14-28	
1516268-2	1992	Independent of its effects on renal haemodynamics and glomerular filtration, angiotensin II (AII) has direct actions on the proximal tubule involving transepithelial Na+, H+, HCO3-, and water reabsorption, ammoniagenesis, gluconeogenesis and renal growth.	Bicarbonates	175-179	angiotensinogen	Homo sapiens	77-91	
1516268-2	1992	Independent of its effects on renal haemodynamics and glomerular filtration, angiotensin II (AII) has direct actions on the proximal tubule involving transepithelial Na+, H+, HCO3-, and water reabsorption, ammoniagenesis, gluconeogenesis and renal growth.	Bicarbonates	175-179	angiotensinogen	Homo sapiens	93-96