PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27920473-11	2016	CONCLUSION: The data strongly suggests that NBC1 is diversely expressed in the pancreas at different developmental stages, where it may exert its functions in pancreatic development especially islet cell growth through HCO3- transport and pH regulation.	Bicarbonates	219-223	solute carrier family 4 member 4	Rattus norvegicus	44-48	
16575514-6	2006	The proteins involved in HCO(3) (-) production, Na(+)/HCO(3) (-) cotransporter (NBC), was found along the BLM but was absent on the MV, whereas carbonic anhydrase II (CA II) was observed on the MV and along the BLM.	Bicarbonates	25-31	solute carrier family 4 member 4	Rattus norvegicus	48-78	
16575514-0	2006	Bicarbonate secretion by rat bile duct brush cells indicated by immunohistochemical localization of CFTR, anion exchanger AE2, Na+/HCO3 -cotransporter, carbonic anhydrase II, Na+/H+ exchangers NHE1 and NHE3, H+/K+-ATPase, and Na+/K+-ATPase.	Bicarbonates	0-11	solute carrier family 4 member 4	Rattus norvegicus	127-150	
16807546-13	2006	The long-term effects of Ang-II in the proximal tubule may be mediated in part by regulation of NBC1 abundance, modifying bicarbonate reabsorption.	Bicarbonates	122-133	solute carrier family 4 member 4	Rattus norvegicus	96-100	
16735752-2	2006	Oocytes expressing rat brain NBCe1-B and exposed to a CO(2)/HCO(3)(-) solution displayed all the hallmarks of an electrogenic Na(+)/HCO(3)(-) cotransporter: (a) a DIDS-sensitive pH(i) recovery following the initial CO(2)-induced acidification, (b) an instantaneous hyperpolarization, and (c) an instantaneous Na(+)-dependent outward current under voltage-clamp conditions (-60 mV).	Bicarbonates	60-69	solute carrier family 4 member 4	Rattus norvegicus	126-155	
16785749-1	2006	Na+-HCO3- cotransporter (NBC1) plays a major role in bicarbonate reabsorption from proximal tubules.	Bicarbonates	53-64	solute carrier family 4 member 4	Rattus norvegicus	25-29	
11095641-1	2000	Immunofluorescence analysis has revealed that electrogenic Na(+)/HCO(3)(-) (NBC1) is expressed in the proximal tubule of rat kidney and in the proximal and distal tubules of the salamander AMBYSTOMA: tigrinum kidney.	Bicarbonates	65-71	solute carrier family 4 member 4	Rattus norvegicus	76-80	
15057604-10	2004	Moreover, the immunolocalization of protein 4.1B was almost the same as that of NBC-1, indicating a possible function as a regulator of ion balance, such as Na(+) and HCO(3)(-) reabsorption.	Bicarbonates	167-173	solute carrier family 4 member 4	Rattus norvegicus	80-85	
14733916-10	2004	The data indicate that the two NH(2)-terminal NBC1 variants are co-expressed in kidney and pancreas, where they may contribute to HCO(3)(-) transport and pH regulation.	Bicarbonates	130-136	solute carrier family 4 member 4	Rattus norvegicus	46-50	
12388414-8	2003	Although exposure of NBC1-expressing oocytes to CO(2)/HCO(3)(-) resulted in immediate hyperpolarization, the NBC4-expressing oocytes did not show any alteration in membrane potential.	Bicarbonates	54-60	solute carrier family 4 member 4	Rattus norvegicus	21-25	
11703600-0	2001	Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading.	Bicarbonates	61-72	solute carrier family 4 member 4	Rattus norvegicus	31-36	
11703600-1	2001	BACKGROUND: Bicarbonate reabsorption in the kidney proximal tubule is predominantly mediated via the apical Na+/H+ exchanger (NHE-3) and basolateral Na+: HCO(-3) cotransporter (NBC-1).	Bicarbonates	12-23	solute carrier family 4 member 4	Rattus norvegicus	149-175	
11703600-1	2001	BACKGROUND: Bicarbonate reabsorption in the kidney proximal tubule is predominantly mediated via the apical Na+/H+ exchanger (NHE-3) and basolateral Na+: HCO(-3) cotransporter (NBC-1).	Bicarbonates	12-23	solute carrier family 4 member 4	Rattus norvegicus	177-182	
9841505-11	1998	HCO3- loading decreased NBC-1 mRNA levels, which were unchanged either by metabolic acidosis or by CDA.	Bicarbonates	0-4	solute carrier family 4 member 4	Rattus norvegicus	24-29	
8013070-11	1994	The contribution of these bicarbonate-dependent pHi regulators, ie, the Na-HCO3 cotransporter and the Cl-HCO3 exchanger, cannot therefore be ignored even under nominally HCO3-free conditions.	Bicarbonates	26-37	solute carrier family 4 member 4	Rattus norvegicus	72-93	
24295739-2	2014	We hypothesized that uterine SLC4A4 expression changes under different sex-steroid influence, therefore may account for the fluctuation in uterine fluid Na(+) and HCO3(-) content throughout the oestrous cycle.	Bicarbonates	163-167	solute carrier family 4 member 4	Rattus norvegicus	29-35	
24295739-12	2014	CONCLUSION: High SLC4A4 expression under estrogen dominance may contribute to the increase in uterine fluid Na(+) and HCO3(-) content, while its low expression under P4 dominance may result in vice versa.	Bicarbonates	118-122	solute carrier family 4 member 4	Rattus norvegicus	17-23	
31569818-6	2019	These changes correlated with a lower expression of ion-exchanger genes, namely, CAII, NBC1, and AE1, which are involved in bicarbonate kidney reabsorption.	Bicarbonates	124-135	solute carrier family 4 member 4	Rattus norvegicus	87-91	
10966933-8	2000	We propose that NBC-1 likely mediates enhanced HCO(3)(-) reabsorption in proximal tubule, mTAL, and inner medullary collecting duct in K(+) deprivation and contributes to the maintenance of metabolic alkalosis in this condition.	Bicarbonates	47-53	solute carrier family 4 member 4	Rattus norvegicus	16-21	
9841505-6	1998	In addition, we describe both the organ and nephron segment distributions and the regulation of NBC-1 mRNA under three models of pH stress: chloride-depletion alkalosis (CDA), metabolic acidosis, and bicarbonate loading.	Bicarbonates	200-211	solute carrier family 4 member 4	Rattus norvegicus	96-101	
24295739-1	2014	UNLABELLED: Oestrogen-induced uterine fluid sodium (Na(+)) and bicarbonate (HCO3(-)) secretion may involve SLC4A4.	Bicarbonates	63-74	solute carrier family 4 member 4	Rattus norvegicus	107-113	
24295739-1	2014	UNLABELLED: Oestrogen-induced uterine fluid sodium (Na(+)) and bicarbonate (HCO3(-)) secretion may involve SLC4A4.	Bicarbonates	76-80	solute carrier family 4 member 4	Rattus norvegicus	107-113