PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20966128-4 2010 We gave aldosterone and NaHCO(3) to increase pendrin-dependent HCO(3)(-) secretion within the connecting tubule and cortical collecting duct, or gave aldosterone and NaHCO(3) plus acetazolamide to increase luminal HCO(3)(-) concentration, [HCO(3)(-)], independent of pendrin. Bicarbonates 63-69 solute carrier family 26, member 4 Mus musculus 45-52 22116364-2 2011 This review focuses on the regulation of blood pressure (BP) by pendrin, an apical Cl(-)/HCO(3)(-) exchanger which mediates HCO(3)(-) secretion and transcellular Cl(-) transport in type B intercalated cells (B-ICs) of the distal nephron. Bicarbonates 89-95 solute carrier family 26, member 4 Mus musculus 64-71 22116370-0 2011 Impact of bicarbonate, ammonium chloride, and acetazolamide on hepatic and renal SLC26A4 expression. Bicarbonates 10-21 solute carrier family 26, member 4 Mus musculus 81-88 22116370-1 2011 SLC26A4 encodes pendrin, a transporter exchanging anions such as chloride, bicarbonate, and iodide. Bicarbonates 75-86 solute carrier family 26, member 4 Mus musculus 0-7 22116370-1 2011 SLC26A4 encodes pendrin, a transporter exchanging anions such as chloride, bicarbonate, and iodide. Bicarbonates 75-86 solute carrier family 26, member 4 Mus musculus 16-23 22116370-3 2011 In the kidney, pendrin is expressed in the distal nephron and accomplishes HCO(3)(-) secretion and Cl(-) reabsorption. Bicarbonates 75-81 solute carrier family 26, member 4 Mus musculus 15-22 20966128-0 2010 Pendrin modulates ENaC function by changing luminal HCO3-. Bicarbonates 52-56 solute carrier family 26, member 4 Mus musculus 0-7 21170868-3 2010 In type B and non-A, non-B intercalated cells, Cl- absorption and HCO3- secretion are accomplished through the apical Na+-independent Cl-/HCO3- exchanger, pendrin. Bicarbonates 66-70 solute carrier family 26, member 4 Mus musculus 155-162 21170868-7 2010 Instead, pendrin changes ENaC abundance and function, at least in part, by altering luminal HCO3-. Bicarbonates 92-96 solute carrier family 26, member 4 Mus musculus 9-16 21073444-2 2011 Pendrin is highly expressed in kidney collecting ducts, where it acts as a chloride/bicarbonate exchanger and thereby contributes to the regulation of acid-base homoeostasis and blood pressure. Bicarbonates 84-95 solute carrier family 26, member 4 Mus musculus 0-7 21073444-5 2011 Combining measurements of pendrin activity with mathematical modelling we found that its affinity for Cl-, HCO3- and OH- varies with intracellular pH, with increased activity at low intracellular pH. Bicarbonates 107-111 solute carrier family 26, member 4 Mus musculus 26-33 22116363-1 2011 The anion exchanger pendrin (Pds, SLC26A4) transports various anions including bicarbonate, chloride and iodide. Bicarbonates 79-90 solute carrier family 26, member 4 Mus musculus 20-27 22116363-1 2011 The anion exchanger pendrin (Pds, SLC26A4) transports various anions including bicarbonate, chloride and iodide. Bicarbonates 79-90 solute carrier family 26, member 4 Mus musculus 34-41 22116363-2 2011 In the kidney, pendrin is exclusively expressed on the luminal pole of bicarbonate-secretory type B intercalated cells. Bicarbonates 71-82 solute carrier family 26, member 4 Mus musculus 15-22 22116363-3 2011 Genetic ablation of pendrin in mice abolishes luminal chloride-bicarbonate exchanger activity from type B intercalated cells suggesting that pendrin is the apical bicarbonate extruding pathway. Bicarbonates 63-74 solute carrier family 26, member 4 Mus musculus 20-27 22116363-3 2011 Genetic ablation of pendrin in mice abolishes luminal chloride-bicarbonate exchanger activity from type B intercalated cells suggesting that pendrin is the apical bicarbonate extruding pathway. Bicarbonates 163-174 solute carrier family 26, member 4 Mus musculus 20-27 22116363-3 2011 Genetic ablation of pendrin in mice abolishes luminal chloride-bicarbonate exchanger activity from type B intercalated cells suggesting that pendrin is the apical bicarbonate extruding pathway. Bicarbonates 163-174 solute carrier family 26, member 4 Mus musculus 141-148 20966128-4 2010 We gave aldosterone and NaHCO(3) to increase pendrin-dependent HCO(3)(-) secretion within the connecting tubule and cortical collecting duct, or gave aldosterone and NaHCO(3) plus acetazolamide to increase luminal HCO(3)(-) concentration, [HCO(3)(-)], independent of pendrin. Bicarbonates 63-69 solute carrier family 26, member 4 Mus musculus 45-52 20966128-5 2010 Following treatment with aldosterone and NaHCO(3), pendrin-null mice had lower urinary pH and [HCO(3)(-)] as well as lower renal ENaC abundance and function than wild-type mice. Bicarbonates 43-49 solute carrier family 26, member 4 Mus musculus 51-58 20966128-11 2010 We conclude that pendrin modulates ENaC abundance and function, at least in part by increasing luminal [HCO(3)(-)] and/or pH. Bicarbonates 104-111 solute carrier family 26, member 4 Mus musculus 17-24 20375274-0 2010 Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct. Bicarbonates 73-77 solute carrier family 26, member 4 Mus musculus 32-39 20375274-10 2010 We conclude that Slc26a4 (pendrin) deletion impairs the secretion of bicarbonate in vivo and reduces apical Cl(-)/HCO(3)(-) exchanger activity in B-IC and non-A, non-B-IC cells in CCD. Bicarbonates 69-80 solute carrier family 26, member 4 Mus musculus 26-33 20375274-0 2010 Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct. Bicarbonates 73-77 solute carrier family 26, member 4 Mus musculus 41-48 20375274-0 2010 Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct. Bicarbonates 112-123 solute carrier family 26, member 4 Mus musculus 32-39 20375274-0 2010 Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct. Bicarbonates 112-123 solute carrier family 26, member 4 Mus musculus 41-48 20375274-4 2010 Pendrin knockout (KO) mice display significantly acidic urine at baseline [pH 5.20 in KO vs. 6.01 in wild type (WT); P < 0.0001] along with elevated serum HCO(3)(-) concentration (27.4 vs. 24 meq/l in KO vs. WT, respectively; P < 0.02), consistent with decreased bicarbonate secretion in vivo. Bicarbonates 269-280 solute carrier family 26, member 4 Mus musculus 0-7 17855646-1 2007 Pendrin is an apical anion exchanger found in type B and nonA-nonB intercalated cells that is involved in bicarbonate secretion. Bicarbonates 106-117 solute carrier family 26, member 4 Mus musculus 0-7 19605545-1 2009 Pendrin is expressed in the apical regions of type B and non-A, non-B intercalated cells, where it mediates Cl(-) absorption and HCO3(-) secretion through apical Cl(-)/HCO3(-) exchange. Bicarbonates 168-172 solute carrier family 26, member 4 Mus musculus 0-7 18565999-0 2008 The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct. Bicarbonates 62-66 solute carrier family 26, member 4 Mus musculus 4-11 18565999-0 2008 The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct. Bicarbonates 62-66 solute carrier family 26, member 4 Mus musculus 87-94 19605545-1 2009 Pendrin is expressed in the apical regions of type B and non-A, non-B intercalated cells, where it mediates Cl(-) absorption and HCO3(-) secretion through apical Cl(-)/HCO3(-) exchange. Bicarbonates 129-133 solute carrier family 26, member 4 Mus musculus 0-7 18209476-2 2008 Bicarbonate secretion is mediated via Pendrin (Slc26a4), which is expressed on the apical membrane of B-ICs and nonA-nonB ICs in the cortical collecting ducts (CCD). Bicarbonates 0-11 solute carrier family 26, member 4 Mus musculus 38-45 18209476-2 2008 Bicarbonate secretion is mediated via Pendrin (Slc26a4), which is expressed on the apical membrane of B-ICs and nonA-nonB ICs in the cortical collecting ducts (CCD). Bicarbonates 0-11 solute carrier family 26, member 4 Mus musculus 47-54 18209476-11 2008 CONCLUSION: CAII deficiency results in a significant decrease in the gene and protein expression of bicarbonate transport proteins from Slc26 gene family - Slc26a4 (pendrin) and Slc26a7. Bicarbonates 100-111 solute carrier family 26, member 4 Mus musculus 156-163 18209476-11 2008 CONCLUSION: CAII deficiency results in a significant decrease in the gene and protein expression of bicarbonate transport proteins from Slc26 gene family - Slc26a4 (pendrin) and Slc26a7. Bicarbonates 100-111 solute carrier family 26, member 4 Mus musculus 165-172 18090665-4 2008 In type B and non-A, non-B intercalated cells chloride absorption and HCO3- secretion are accomplished through the apical sodium-independent Cl-/HCO3- exchanger pendrin. Bicarbonates 70-74 solute carrier family 26, member 4 Mus musculus 161-168 17200157-0 2007 Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels. Bicarbonates 16-20 solute carrier family 26, member 4 Mus musculus 8-15 17299139-5 2007 Pendrin in the cochlea was characterized as a formate-permeable and DIDS-sensitive anion exchanger that is likely to mediate HCO(3)(-) secretion into endolymph. Bicarbonates 125-131 solute carrier family 26, member 4 Mus musculus 0-7 17055311-1 2006 Pendrin is a membrane transport protein which functions as the transporter of chloride, bicarbonate, formate, and iodide. Bicarbonates 88-99 solute carrier family 26, member 4 Mus musculus 0-7 17120771-1 2006 SLC26A4 (pendrin, PDS) is a Na+-independent, Cl-/HCO3-/OH- exchanger that is expressed in the apical regions of type B and non-A, non-B intercalated cells within the cortical collecting duct (CCD), the connecting tubule and the distal convoluted tubule where it mediates HCO3- secretion and Cl- absorption. Bicarbonates 49-53 solute carrier family 26, member 4 Mus musculus 0-7 17120771-6 2006 Moreover, during NaCl restriction or following DOCP treatment, Slc26a4-/- mice have a higher serum HCO3- than wild type mice from an impaired ability to excrete OH- equivalents. Bicarbonates 99-103 solute carrier family 26, member 4 Mus musculus 63-70 17120771-1 2006 SLC26A4 (pendrin, PDS) is a Na+-independent, Cl-/HCO3-/OH- exchanger that is expressed in the apical regions of type B and non-A, non-B intercalated cells within the cortical collecting duct (CCD), the connecting tubule and the distal convoluted tubule where it mediates HCO3- secretion and Cl- absorption. Bicarbonates 49-53 solute carrier family 26, member 4 Mus musculus 9-16 16144965-8 2005 However, urinary pH and Pco(2) were much lower in Slc26a4 null relative to wild-type mice due to reduced urinary buffering of secreted H(+) by HCO(3)(-). Bicarbonates 143-149 solute carrier family 26, member 4 Mus musculus 50-57 12427135-3 2002 Recently pendrin has been localized to the apical side of non-type A intercalated cells of the cortical collecting duct, and reduced bicarbonate secretion was demonstrated in a pendrin knockout mouse model. Bicarbonates 133-144 solute carrier family 26, member 4 Mus musculus 177-184 12427135-10 2002 In contrast, following oral bicarbonate loading pendrin was found exclusively in the apical membrane and the relative number of pendrin positive cells increased. Bicarbonates 28-39 solute carrier family 26, member 4 Mus musculus 48-55 12427135-10 2002 In contrast, following oral bicarbonate loading pendrin was found exclusively in the apical membrane and the relative number of pendrin positive cells increased. Bicarbonates 28-39 solute carrier family 26, member 4 Mus musculus 128-135 12427135-11 2002 CONCLUSIONS: These results are in agreement with a potential role of pendrin in bicarbonate secretion and regulation of acid-base transport in the cortical collecting duct. Bicarbonates 80-91 solute carrier family 26, member 4 Mus musculus 69-76 35224991-1 2022 Pendrin is an intercalated cell Cl-/HCO3- exchanger thought to participate in K+-sparing NaCl absorption. Bicarbonates 36-40 solute carrier family 26, member 4 Mus musculus 0-7 11274445-0 2001 Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Bicarbonates 117-128 solute carrier family 26, member 4 Mus musculus 0-7 11274445-7 2001 Furthermore, pendrin was detected exclusively within the subpopulation of intercalated cells that express the H(+)-ATPase but not the anion exchanger 1 (AE1) and that are thought to mediate bicarbonate secretion. Bicarbonates 190-201 solute carrier family 26, member 4 Mus musculus 13-20 11274445-11 2001 Together, these studies indicate that pendrin is an apical anion transporter in intercalated cells of CCDs and has an essential role in renal bicarbonate secretion. Bicarbonates 142-153 solute carrier family 26, member 4 Mus musculus 38-45 12411484-3 2002 In contrast, CFTR markedly activates Cl(-) and OH(-)/HCO(3)(-) transport by members of the SLC26 family DRA, SLC26A6 and pendrin. Bicarbonates 53-59 solute carrier family 26, member 4 Mus musculus 121-128 34252449-5 2021 The abundance of the chloride/bicarbonate exchanger pendrin was increased, likely explaining the acidosis. Bicarbonates 30-41 solute carrier family 26, member 4 Mus musculus 52-59 32703846-6 2020 In perfused cortical collecting ducts, secretin stimulated pendrin-dependent Cl-/HCO3 - exchange. Bicarbonates 81-87 solute carrier family 26, member 4 Mus musculus 59-66 35173044-10 2022 This is caused by defective HCO3 - secretion in the beta-intercalated cells of the collecting duct that requires both the cystic fibrosis transmembrane conductance regulator (CFTR) and pendrin for normal function (P. Berg et al., J. Bicarbonates 28-32 solute carrier family 26, member 4 Mus musculus 185-192 33186222-1 2021 PURPOSE OF REVIEW: Pendrin resides on the luminal membrane of type B intercalated cells in the renal collecting tubule system mediating the absorption of chloride in exchange for bicarbonate. Bicarbonates 179-190 solute carrier family 26, member 4 Mus musculus 19-26 26538443-1 2016 Pendrin is a Na(+)-independent Cl(-)/HCO3(-) exchanger found in the apical regions of type B and non-A, non-B intercalated cells within the aldosterone-sensitive region of the nephron, i.e., the distal convoluted tubule (DCT), the connecting tubule (CNT), and the cortical collecting duct (CCD). Bicarbonates 37-41 solute carrier family 26, member 4 Mus musculus 0-7 30816203-1 2019 In the renal collecting duct, intercalated cells regulate acid-base balance by effluxing protons through the v-H+-ATPase, and bicarbonate via apical pendrin or the basolateral kidney anion exchanger 1 (kAE1). Bicarbonates 126-137 solute carrier family 26, member 4 Mus musculus 149-156 30146013-6 2018 However, these cells can also mediate thiazide-sensitive sodium chloride absorption when the pendrin-dependent apical chloride influx is coupled to apical sodium influx by the sodium-driven chloride/bicarbonate exchanger. Bicarbonates 199-210 solute carrier family 26, member 4 Mus musculus 93-100 29773687-9 2018 Moreover, pendrin gene ablation eliminated the increase in BP observed in global Nedd4-2 knockout mice.Conclusions IC Nedd4-2 regulates Cl-/HCO3- exchange in ICs., Nedd4-2 gene ablation increases BP in part through its action in these cells. Bicarbonates 140-144 solute carrier family 26, member 4 Mus musculus 10-17 32034107-2 2020 The chloride-bicarbonate exchanger pendrin in beta-intercalated cells, along with sodium chloride cotransporter (NCC) in distal convoluted tubules, complementarily regulate sodium chloride handling, which is controlled by the renin-angiotensin-aldosterone system. Bicarbonates 13-24 solute carrier family 26, member 4 Mus musculus 35-42 30146013-5 2018 These latter cells exchange intracellular bicarbonate for external chloride through pendrin, and therefore, account for renal base excretion. Bicarbonates 42-53 solute carrier family 26, member 4 Mus musculus 84-91 28064162-1 2017 Background: Pendrin, the chloride/bicarbonate exchanger of beta-intercalated cells of the renal connecting tubule and the collecting duct, plays a key role in NaCl reabsorption by the distal nephron. Bicarbonates 34-45 solute carrier family 26, member 4 Mus musculus 12-19 28559854-3 2017 Several members of the Slc26 gene family (Slc26a1, Slc26a3, Slc26a4, Slc26a6, and Slc26a7), which exhibit bicarbonate transport activities, have been suggested by previous studies to be involved in maturation-stage amelogenesis, especially the key process of pH regulation. Bicarbonates 106-117 solute carrier family 26, member 4 Mus musculus 60-67 26538443-2 2016 Type B intercalated cells mediate Cl(-) absorption and HCO3(-) secretion primarily through pendrin-mediated Cl(-)/HCO3(-) exchange. Bicarbonates 55-59 solute carrier family 26, member 4 Mus musculus 91-98 26538443-2 2016 Type B intercalated cells mediate Cl(-) absorption and HCO3(-) secretion primarily through pendrin-mediated Cl(-)/HCO3(-) exchange. Bicarbonates 114-118 solute carrier family 26, member 4 Mus musculus 91-98 26538443-4 2016 In the absence of pendrin-mediated HCO3(-) secretion, an enhanced alkalosis is observed following aldosterone or NaHCO3 administration. Bicarbonates 35-39 solute carrier family 26, member 4 Mus musculus 18-25 26538443-7 2016 Pendrin changes ENaC activity by changing both channel open probability (Po) and surface density (N), at least partly by altering luminal HCO3(-) and ATP concentration. Bicarbonates 138-142 solute carrier family 26, member 4 Mus musculus 0-7 26394631-4 2015 Solute carrier (Slc) family 26A encodes different anion exchangers that exchange Cl(-)/HCO3 (-), including Slc26a3/Dra, Slc26a6/Pat-1, and Slc26a4/pendrin. Bicarbonates 87-91 solute carrier family 26, member 4 Mus musculus 139-146 26394631-4 2015 Solute carrier (Slc) family 26A encodes different anion exchangers that exchange Cl(-)/HCO3 (-), including Slc26a3/Dra, Slc26a6/Pat-1, and Slc26a4/pendrin. Bicarbonates 87-91 solute carrier family 26, member 4 Mus musculus 147-154 23637202-14 2013 Instead, pendrin changes ENaC abundance and function, at least in part, by altering luminal HCO3(-). Bicarbonates 92-96 solute carrier family 26, member 4 Mus musculus 9-16 25069981-4 2014 One of the genes most highly upregulated in a PT-dependent manner encodes an epithelial transporter of bicarbonate, chloride, and thiocyanate, named pendrin, that contributes to asthma pathology. Bicarbonates 103-114 solute carrier family 26, member 4 Mus musculus 149-156 23637202-11 2013 Cl(-) absorption increases markedly with angiotensin and aldosterone administration, largely by upregulating the Na(+)-independent Cl(-)/HCO3(-) exchanger pendrin. Bicarbonates 137-141 solute carrier family 26, member 4 Mus musculus 155-162 25281699-1 2015 The [Formula: see text] exchanger pendrin (SLC26A4, PDS) is located on the apical membrane of B-intercalated cells in the kidney cortical collecting duct and the connecting tubules and mediates the secretion of bicarbonate and the reabsorption of chloride. Bicarbonates 211-222 solute carrier family 26, member 4 Mus musculus 34-41 25281699-1 2015 The [Formula: see text] exchanger pendrin (SLC26A4, PDS) is located on the apical membrane of B-intercalated cells in the kidney cortical collecting duct and the connecting tubules and mediates the secretion of bicarbonate and the reabsorption of chloride. Bicarbonates 211-222 solute carrier family 26, member 4 Mus musculus 43-50 25281699-2 2015 Given its dual function of bicarbonate secretion and chloride reabsorption in the distal tubules, it was thought that pendrin plays important roles in systemic acid-base balance and electrolyte and vascular volume homeostasis under basal conditions. Bicarbonates 27-38 solute carrier family 26, member 4 Mus musculus 118-125 25668022-1 2015 Pendrin is a Na(+)-independent Cl(-)/HCO3(-) exchanger that localizes to type B and non-A, non-B intercalated cells, which are expressed within the aldosterone-sensitive region of the nephron, i.e., the distal convoluted tubule, the connecting tubule, and the cortical collecting duct. Bicarbonates 37-41 solute carrier family 26, member 4 Mus musculus 0-7 25668022-2 2015 Type B cells mediate Cl(-) absorption and HCO3(-) secretion primarily through pendrin-mediated Cl(-)/HCO3(-) exchange. Bicarbonates 42-46 solute carrier family 26, member 4 Mus musculus 78-85 25668022-2 2015 Type B cells mediate Cl(-) absorption and HCO3(-) secretion primarily through pendrin-mediated Cl(-)/HCO3(-) exchange. Bicarbonates 101-105 solute carrier family 26, member 4 Mus musculus 78-85 25668022-4 2015 The pendrin-mediated Cl(-)/HCO3(-) exchange process is greatly upregulated in models of metabolic alkalosis, such as following aldosterone administration or dietary NaHCO3 loading. Bicarbonates 27-31 solute carrier family 26, member 4 Mus musculus 4-11 25668022-8 2015 Instead, pendrin changes ENaC abundance and function at least in part by altering luminal HCO3(-) and ATP concentrations. Bicarbonates 90-94 solute carrier family 26, member 4 Mus musculus 9-16 25668022-10 2015 This review summarizes the contribution of the Cl(-)/HCO3(-) exchanger pendrin in distal nephron function. Bicarbonates 53-57 solute carrier family 26, member 4 Mus musculus 71-78 21873623-1 2012 BACKGROUND: The epithelial calcium channel (ECaC) (TRPV5) and the Cl-/HCO3- exchanger pendrin (SLC26A4) are expressed on the apical membrane of tubular cells in the distal nephron and play essential roles in calcium re-absorption and bicarbonate secretion, respectively, in the kidney. Bicarbonates 234-245 solute carrier family 26, member 4 Mus musculus 86-93 21873623-1 2012 BACKGROUND: The epithelial calcium channel (ECaC) (TRPV5) and the Cl-/HCO3- exchanger pendrin (SLC26A4) are expressed on the apical membrane of tubular cells in the distal nephron and play essential roles in calcium re-absorption and bicarbonate secretion, respectively, in the kidney. Bicarbonates 234-245 solute carrier family 26, member 4 Mus musculus 95-102 21873623-5 2012 Subjecting the pendrin WT and KO mice to oral bicarbonate loading for 12 days increased the urine pH to ~8 in both genotypes, normalized the expression of ECaC and Na/Ca exchanger and reduced the urine calcium excretion in pendrin-null mice to levels comparable to WT mice. Bicarbonates 46-57 solute carrier family 26, member 4 Mus musculus 15-22 21873623-5 2012 Subjecting the pendrin WT and KO mice to oral bicarbonate loading for 12 days increased the urine pH to ~8 in both genotypes, normalized the expression of ECaC and Na/Ca exchanger and reduced the urine calcium excretion in pendrin-null mice to levels comparable to WT mice. Bicarbonates 46-57 solute carrier family 26, member 4 Mus musculus 223-230 22243245-2 2011 Solute carrier family 26A member 4 (SLC26A4, or pendrin) is an anion exchanger for chloride, bicarbonate, iodine, and formate. Bicarbonates 93-104 solute carrier family 26, member 4 Mus musculus 0-34 22243245-2 2011 Solute carrier family 26A member 4 (SLC26A4, or pendrin) is an anion exchanger for chloride, bicarbonate, iodine, and formate. Bicarbonates 93-104 solute carrier family 26, member 4 Mus musculus 36-43 22243245-2 2011 Solute carrier family 26A member 4 (SLC26A4, or pendrin) is an anion exchanger for chloride, bicarbonate, iodine, and formate. Bicarbonates 93-104 solute carrier family 26, member 4 Mus musculus 48-55 21965328-2 2011 SLC26A4 encodes pendrin, an anion-base exchanger expressed in inner ear epithelial cells that secretes HCO3- into endolymph. Bicarbonates 103-107 solute carrier family 26, member 4 Mus musculus 0-7 21965328-2 2011 SLC26A4 encodes pendrin, an anion-base exchanger expressed in inner ear epithelial cells that secretes HCO3- into endolymph. Bicarbonates 103-107 solute carrier family 26, member 4 Mus musculus 16-23