PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29302216-7	2018	These results suggested that like IRBIT, PP1 was another novel regulator of HCO3- secretion in several types of epithelia.	Bicarbonates	76-80	adenosylhomocysteinase like 1	Homo sapiens	34-39	
33727633-0	2021	Both IRBIT and long-IRBIT bind to and coordinately regulate Cl-/HCO3- exchanger AE2 activity through modulating the lysosomal degradation of AE2.	Bicarbonates	64-68	adenosylhomocysteinase like 1	Homo sapiens	5-10	
33727633-0	2021	Both IRBIT and long-IRBIT bind to and coordinately regulate Cl-/HCO3- exchanger AE2 activity through modulating the lysosomal degradation of AE2.	Bicarbonates	64-68	adenosylhomocysteinase like 1	Homo sapiens	20-25	
24518248-2	2014	Unexpectedly, many functions have subsequently been identified for IRBIT including the activation of multiple ion channels and ion transporters, such as the Na(+)/HCO3(-) co-transporter NBCe1-B, the Na(+)/H(+) exchanger NHE3, the Cl(-) channel cystic fibrosis transmembrane conductance regulator (CFTR), and the Cl(-)/HCO3(-) exchanger Slc26a6.	Bicarbonates	163-167	adenosylhomocysteinase like 1	Homo sapiens	67-72	
24472682-1	2014	Although AHCYL2 (long-IRBIT) is highly homologous to IRBIT, which regulates ion-transporting proteins including the electrogenic Na(+)-HCO3(-) cotransporter NBCe1-B, its functions are poorly understood.	Bicarbonates	135-139	adenosylhomocysteinase like 1	Homo sapiens	53-58	
24472682-1	2014	Although AHCYL2 (long-IRBIT) is highly homologous to IRBIT, which regulates ion-transporting proteins including the electrogenic Na(+)-HCO3(-) cotransporter NBCe1-B, its functions are poorly understood.	Bicarbonates	135-139	adenosylhomocysteinase like 1	Homo sapiens	22-27	
23431199-2	2013	HCO3(-) secretion is highly regulated, with the WNK/SPAK kinase pathway setting the resting state and the IRBIT/PP1 pathway setting the stimulated state.	Bicarbonates	0-4	adenosylhomocysteinase like 1	Homo sapiens	106-111