PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23784542-3	2013	Carbachol (CCh) stimulation of the small intestine results in gel-forming mucin secretion from goblet cells, something that requires adjacent enterocytes to secrete chloride and bicarbonate for proper mucin formation.	Bicarbonates	178-189	LOC100508689	Homo sapiens	74-79	
30742493-1	2019	Bicarbonate facilitates mucin unpacking and bacterial killing; however, its transport mechanisms in the airways are not well understood.	Bicarbonates	0-11	LOC100508689	Homo sapiens	24-29	
30431338-5	2018	The bicarbonate raises the pH and removes calcium from the N terminus of MUC5B, allowing the mucin to be pulled out into a linear polymer.	Bicarbonates	4-15	LOC100508689	Homo sapiens	93-98	
27786259-0	2016	Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.	Bicarbonates	38-49	LOC100508689	Homo sapiens	71-76	
27786259-4	2016	Importantly, mucin release, elicited by purinergic stimulation, requires the presence of bicarbonate in the basolateral solution and is defective in cells derived from cystic fibrosis patients.	Bicarbonates	89-100	LOC100508689	Homo sapiens	13-18	
26134505-4	2015	We have recently shown that bicarbonate ions passing through CFTR are necessary for proper unfolding of the MUC2 mucin, thus highlighting the importance of bicarbonate ion transport via the CFTR and the ability of these ions to raise the pH and chelate calcium bound to the mucin as the important steps in forming normal mucus.	Bicarbonates	28-39	LOC100508689	Homo sapiens	113-118	
26134505-4	2015	We have recently shown that bicarbonate ions passing through CFTR are necessary for proper unfolding of the MUC2 mucin, thus highlighting the importance of bicarbonate ion transport via the CFTR and the ability of these ions to raise the pH and chelate calcium bound to the mucin as the important steps in forming normal mucus.	Bicarbonates	28-39	LOC100508689	Homo sapiens	274-279	
26134505-4	2015	We have recently shown that bicarbonate ions passing through CFTR are necessary for proper unfolding of the MUC2 mucin, thus highlighting the importance of bicarbonate ion transport via the CFTR and the ability of these ions to raise the pH and chelate calcium bound to the mucin as the important steps in forming normal mucus.	Bicarbonates	156-167	LOC100508689	Homo sapiens	113-118	
23784542-3	2013	Carbachol (CCh) stimulation of the small intestine results in gel-forming mucin secretion from goblet cells, something that requires adjacent enterocytes to secrete chloride and bicarbonate for proper mucin formation.	Bicarbonates	178-189	LOC100508689	Homo sapiens	201-206	
20926781-0	2010	Role of epithelial HCO3- transport in mucin secretion: lessons from cystic fibrosis.	Bicarbonates	19-23	LOC100508689	Homo sapiens	38-43	
23125206-3	2012	This packing allows an ordered release and a normal mucin expansion when calcium is removed and pH increased by bicarbonate.	Bicarbonates	112-123	LOC100508689	Homo sapiens	52-57	
35635440-3	2022	Bicarbonate is critical for correct mucin deployment and there is increasing interest in understanding its role in airway physiology, particularly in the initiation of lung disease in children affected by cystic fibrosis, in the absence of detectable bacterial infection.	Bicarbonates	0-11	LOC100508689	Homo sapiens	36-41