PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8103010-9 1993 The somatostatin analogue exerts a long-lasting inhibitory action on gastric acid, pancreatic enzyme and bicarbonate secretion as well as on bile flow. Bicarbonates 105-116 somatostatin Homo sapiens 4-16 2888607-6 1987 Bicarbonate concentration was slightly but significantly reduced only by the two highest doses of somatostatin. Bicarbonates 0-11 somatostatin Homo sapiens 98-110 1967642-8 1990 Mucosal lsc responses to SS-14 were absent in tissues bathed in HCO3-free media. Bicarbonates 64-68 somatostatin Homo sapiens 25-30 1351858-2 1992 To evaluate the possibility that the increased levels of S-28 post cibum might modulate the release of enzymes and bicarbonate from the exocrine pancreas, S-28 was infused intravenously into healthy volunteers to levels seen after food intake. Bicarbonates 115-126 somatostatin Homo sapiens 57-61 1351858-3 1992 During S-28 infusion, the output of lipase, trypsin, amylase, and bicarbonate stimulated by either exogenous cholecystokinin octapeptide or endogenous signals from intraduodenal administration of tryptophan or a mixture of amino acids was significantly reduced. Bicarbonates 66-77 somatostatin Homo sapiens 7-11 2888607-9 1987 The results demonstrate that: (1) the administration of somatostatin at a low dose level does not affect human exocrine pancreatic secretion, at least under the experimental conditions of this study; and (2) the administration of larger doses of somatostatin inhibits pancreatic secretion of both protein and bicarbonate dose-dependently. Bicarbonates 309-320 somatostatin Homo sapiens 246-258 7907564-4 1994 Somatostatin probably inhibits pancreatic exocrine secretion by a variety of mechanisms which depend on the species and the type of secretion studied (postprandial vs. interdigestive secretion, protein vs. bicarbonate secretion): Somatostatin may act via inhibition of the release of circulating hormones such as cholecystokinin (CCK) and secretin or via intrapancreatic inhibition of the release or action of CCK. Bicarbonates 206-217 somatostatin Homo sapiens 0-12 6131942-1 1983 Somatostatin-producing cerebral cortical cell cultures were grown in either high- (33 mM) or low-glucose (5 mM) medium and then exposed to short repetitive changes of high- or low-glucose Krebs-Ringer"s bicarbonate buffer. Bicarbonates 203-214 somatostatin Homo sapiens 0-12