PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22857012-0 2012 Probing ligand-binding modes and binding mechanisms of benzoxazole-based amide inhibitors with soluble epoxide hydrolase by molecular docking and molecular dynamics simulation. Benzoxazoles 55-66 epoxide hydrolase 2 Homo sapiens 95-120 22857012-3 2012 A set of six benzoxazole-based amide inhibitors binding to sEH has been studied through molecular docking, MD simulation, free energy calculations, and energy decomposition analysis. Benzoxazoles 13-24 epoxide hydrolase 2 Homo sapiens 59-62 21302953-2 2011 X-ray crystal structures revealed unique interactions for a benzoxazole template in addition to the conserved hydrogen bonds with the catalytic machinery of sEH. Benzoxazoles 60-71 epoxide hydrolase 2 Homo sapiens 157-160 21302953-7 2011 The SAR understanding of the benzoxazole template provides valuable insights into discovery of novel sEH inhibitors as therapeutic agents. Benzoxazoles 29-40 epoxide hydrolase 2 Homo sapiens 101-104