PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16600024-6	2006	F-met-leu-phe increased CD11b, CD35 and CD18 and decreased CD62L expression in all groups, with a greater CD35 increase in severe asthma.	N-Formylmethionine Leucyl-Phenylalanine	0-13	integrin subunit beta 2	Homo sapiens	40-44	
10080540-4	1999	In low-concentration gels (<0.6 mg/mL), anti-CD18 had a significant influence on PMN migration, increasing motility in unstimulated PMN by 90% at 0.3 mg/mL collagen, and decreasing motility in N-formyl-methionyl-leucyl-phenylalanine (fMLP)-stimulated PMN by 70% at 0.4 mg/mL collagen.	N-Formylmethionine Leucyl-Phenylalanine	237-241	integrin subunit beta 2	Homo sapiens	43-52	
11834990-6	2002	RESULTS: Stimulation with f-met-leu-phe increased cell volume, respiratory burst, aggregation, and CD18 expression.	N-Formylmethionine Leucyl-Phenylalanine	26-39	integrin subunit beta 2	Homo sapiens	99-103	
9009313-7	1997	In addition, CneF, GXM, and GalXM but not MP significantly blocked the binding of the anti-CD18 MAb to CD18 on the surface of unactivated and formyl methionyl leucyl phenylalanine-activated PMN as determined by indirect immunofluorescence staining and flow cytometric analysis.	N-Formylmethionine Leucyl-Phenylalanine	142-179	integrin subunit beta 2	Homo sapiens	91-95	
9009313-7	1997	In addition, CneF, GXM, and GalXM but not MP significantly blocked the binding of the anti-CD18 MAb to CD18 on the surface of unactivated and formyl methionyl leucyl phenylalanine-activated PMN as determined by indirect immunofluorescence staining and flow cytometric analysis.	N-Formylmethionine Leucyl-Phenylalanine	142-179	integrin subunit beta 2	Homo sapiens	103-107	
1982728-5	1990	There was decreased expression of CD11b/CD18 in pseudo-Pelger granulocytes with respect to controls (P less than 0.001) after stimulation with formyl-met-leu-phe (FMLP).	N-Formylmethionine Leucyl-Phenylalanine	143-161	integrin subunit beta 2	Homo sapiens	40-44	
8660846-2	1996	We examined the topographical distribution of CD18 on human neutrophils in relation with shapes changes and movements induced by stimulation with 10(-8) M N-formylmethionyl-leucyl-phenylalanine (fMLP) and 10(-7) M phorbol myristate acetate (PMA).	N-Formylmethionine Leucyl-Phenylalanine	155-193	integrin subunit beta 2	Homo sapiens	46-50	
7531948-5	1995	Butanol and PTX also significantly reduced the upregulation of CD11b/CD18 by f-methionyl-leucyl-phenylalanine (fMLP) and platelet-activating factor (PAF) but not by phorbol myristate acetate (PMA).	N-Formylmethionine Leucyl-Phenylalanine	111-115	integrin subunit beta 2	Homo sapiens	69-73	
8100744-3	1993	Levels of labelled CD11b and CD18 increased after activation with the chemotactic peptide formyl-methionyl-leucyl phenylalanine (fMLP) in a dose- and time-dependent manner, but CD11a did not, indicating that CD11a would not be a useful marker of neutrophil activation.	N-Formylmethionine Leucyl-Phenylalanine	90-127	integrin subunit beta 2	Homo sapiens	29-33	
1979013-4	1990	When neutrophils were incubated in the presence of cycloheximide, they progressively lost their ability to generate reactive oxidants in response to fMet-Leu-Phe so that by 5 h incubation with this inhibitor they could only generate about 25% of the oxidative response stimulated in untreated cells, and the expression of CD16 and CD18 was grossly impaired.	N-Formylmethionine Leucyl-Phenylalanine	149-161	integrin subunit beta 2	Homo sapiens	331-335	
3123109-2	1988	In the neutrophil, the surface expression of the CD11/CD18 complex is up-modulated (Mo1 greater than p150,95 much greater than LFA-1) by stimulatory factors that include calcium ionophore A23187, phorbol myristate acetate (PMA), and N-L-formyl-L-leucyl-L-phenylalanine (fMLP).	N-Formylmethionine Leucyl-Phenylalanine	270-274	integrin subunit beta 2	Homo sapiens	54-58	
6096477-4	1984	A latent pool of Mac-1 that can be expressed on granulocyte surfaces in response to secretory stimuli, such as f-Met-Leu-Phe, was also lacking in patients.	N-Formylmethionine Leucyl-Phenylalanine	111-124	integrin subunit beta 2	Homo sapiens	17-22