PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34138966-7 2021 Our study also demonstrates that brazilin and theaflavin-3,3"-digallate, and to a still greater extent, curcumin, decrease the activity of transmembrane serine protease 2 both in cell-free and cell-based assays. Curcumin 104-112 transmembrane serine protease 2 Homo sapiens 139-170 18719366-6 2008 Of note, curcumin downregulated transcript encoded by the potentially causal TMPRSS2-ERG gene fusion, a common oncogenic alteration noted in 50-70% of prostate cancer patients. Curcumin 9-17 transmembrane serine protease 2 Homo sapiens 77-84 33375616-7 2020 Several well-studied drugs can downregulate the expression of TMPRSS2 in human cells, including acetaminophen (paracetamol) and curcumin. Curcumin 128-136 transmembrane serine protease 2 Homo sapiens 62-69