PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32156842-7	2020	Based on the attained results, mean serum levels of VCAM-1 in the nano-curcumin group were significantly reduced at the end of the study, compared with the placebo group (P < .001).	Curcumin	71-79	vascular cell adhesion molecule 1	Homo sapiens	52-58	
31665675-7	2019	Therefore, combined curcumin and luteolin at physiological concentrations synergistically inhibits TNF-alpha-induced monocytes adhesion to endothelial cells and expressions of MCP-1 and VCAM-1 via suppressing NF-kappaB translocation into the nucleus.	Curcumin	20-28	vascular cell adhesion molecule 1	Homo sapiens	186-192	
31665675-5	2019	We also found that TNF-alpha-enhanced protein expressions of vascular cell adhesion molecule 1 (VCAM-1), monocyte chemotactic protein-1 (MCP-1) and nuclear factor (NF)-kappaB translocation were synergistically reduced by the combined curcumin and luteolin in EA.hy 926 cells while the individual chemical did not have this inhibitory effect.	Curcumin	234-242	vascular cell adhesion molecule 1	Homo sapiens	61-94	
19520742-8	2009	Tumor necrosis factor (TNF)-alpha/lipopolysaccharide (LPS)-induced VCAM-1 expression in HIMEC was suppressed by Akt small-interfering RNA, curcumin, and inhibitors of NF-kappaB (SN-50), p38 MAPK (SB-203580) and PI 3-kinase/Akt (LY-294002).	Curcumin	139-147	vascular cell adhesion molecule 1	Homo sapiens	67-73	
28228072-7	2017	Specifically, curcumin"s anti-inflammatory effects are thought to be caused by reducing trans-endothelial monocyte migration by reduction of mRNA and protein expression of intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and P-selectin and by modulating NFkappaB, JNK, p38 and STAT-3 in endothelial cells.	Curcumin	14-22	vascular cell adhesion molecule 1	Homo sapiens	207-240	
23313051-4	2013	CCN4-induced VCAM-1 expression was attenuated by alphavbeta5 or alpha6beta1 integrin antibody, Syk inhibitor, PKCdelta inhibitor (rottlerin), JNK inhibitor (SP600125), and AP-1 inhibitors (curcumin and tanshinone).	Curcumin	189-197	vascular cell adhesion molecule 1	Homo sapiens	13-19	
23185512-4	2012	CCL2-mediated VCAM-1 expression was attenuated by CCR2 inhibitor (RS102895), PKCdelta inhibitor (rottlerin), p38MAPK inhibitor (SB203580), and AP-1 inhibitors (curcumin and tanshinone IIA).	Curcumin	160-168	vascular cell adhesion molecule 1	Homo sapiens	14-20	
28713935-11	2017	Curcumin induced NF-kappaB, cell adhesion molecule 1 and vascular cell adhesion protein 1 expression.	Curcumin	0-8	vascular cell adhesion molecule 1	Homo sapiens	57-89	
22183741-0	2012	Curcumin attenuates TNF-alpha-induced expression of intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and proinflammatory cytokines in human endometriotic stromal cells.	Curcumin	0-8	vascular cell adhesion molecule 1	Homo sapiens	87-120	
22183741-5	2012	Endometriotic stromal cells treated with curcumin showed marked suppression of TNF-alpha-induced mRNA expression of ICAM-1 and VCAM-1.	Curcumin	41-49	vascular cell adhesion molecule 1	Homo sapiens	127-133	
22183741-6	2012	Curcumin treatment also significantly decreased the TNF-alpha-induced cell surface and total protein expression of ICAM-1 and VCAM-1 in a dose-dependent manner.	Curcumin	0-8	vascular cell adhesion molecule 1	Homo sapiens	126-132	
19520742-0	2009	Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin.	Curcumin	164-172	vascular cell adhesion molecule 1	Homo sapiens	0-33	
19520742-12	2009	In conclusion, curcumin inhibited the expression of VCAM-1 in HIMECs through blockade of Akt, p38 MAPK, and NF-kappaB.	Curcumin	15-23	vascular cell adhesion molecule 1	Homo sapiens	52-58	
9586949-4	1998	Pretreatment of EC for 1 hr with curcumin completely blocked their adhesion to monocytes, as well as the cell surface expression of ICAM-1, VCAM-1, and ELAM-1 in EC.	Curcumin	33-41	vascular cell adhesion molecule 1	Homo sapiens	140-146	
18182168-6	2008	LPS-induced VCAM-1 expression was also blocked by pretreatment with curcumin (a p300 inhibitor) or transfection with p300 siRNA.	Curcumin	68-76	vascular cell adhesion molecule 1	Homo sapiens	12-18	
10576620-2	1999	We demonstrate here that out of three compounds, viz diferuloylmethane, p-coumaroylferuloylmethane and di-p-coumaroylmethane, present in the ethyl acetate extract of Curcuma longa, diferuloylmethane is most potent in inhibiting TNF-alpha induced expression of ICAM-1, VCAM-1 and E-selectin on human umbilical vein endothelial cells.	Curcumin	181-198	vascular cell adhesion molecule 1	Homo sapiens	268-274	
16288471-8	2006	Most surprisingly, VCAM-1 expression was also significantly blocked by a selective inhibitor of p300, curcumin.	Curcumin	102-110	vascular cell adhesion molecule 1	Homo sapiens	19-25	
34586536-2	2022	The purpose from this study was to determine effects of curcumin nanoparticle into phytosomal formulation (PC) on the relative expression of DSPP, VEGF-A, HLA-G5, VCAM1, RelA and STAT3 genes which are among the most important factors influencing processes of immunomodulatory and tissue regenerative by DPSCs.	Curcumin	56-64	vascular cell adhesion molecule 1	Homo sapiens	163-168