PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15534862-4 2004 The highest DNA adduct levels were found in CYP1A1-expressing V79MZh1A1 cells after DBC and MeDBC treatment (24.5 +/- 7.2 and 16.2 +/- 3.6 adducts/10(8) nucleotides, respectively). 7H-dibenzo(c,g)carbazole 84-87 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 44-50 21809388-0 2011 Genotoxicity of 7H-dibenzo[c,g]carbazole and its tissue-specific derivatives in human hepatoma HepG2 cells is related to CYP1A1/1A2 expression. 7H-dibenzo(c,g)carbazole 16-40 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 121-127 23639521-0 2013 Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation. 7H-dibenzo(c,g)carbazole 103-127 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 23-41 22306306-3 2012 HaCaT cells mainly express cytochrome P4501A1 (CYP1A1), which is involved in metabolism of DBC and N-MeDBC, but not DiMeDBC [10]. 7H-dibenzo(c,g)carbazole 91-94 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 27-45 22306306-3 2012 HaCaT cells mainly express cytochrome P4501A1 (CYP1A1), which is involved in metabolism of DBC and N-MeDBC, but not DiMeDBC [10]. 7H-dibenzo(c,g)carbazole 91-94 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 47-53 21809388-7 2011 Our data clearly demonstrated differences in the mechanisms involved in the biological activity of DiMeDBC and N-MeDBC in human hepatoma cells; the genotoxicity of these DBC derivatives is closely related to CYP1A1/2 expression. 7H-dibenzo(c,g)carbazole 103-106 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 208-214 17166882-5 2007 DBC metabolism by the human CYP1 enzymes was examined in vitro using Supersomestrade mark. 7H-dibenzo(c,g)carbazole 0-3 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 28-32 17166882-0 2007 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes. 7H-dibenzo(c,g)carbazole 0-24 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 59-63 17166882-6 2007 Each mouse CYP1, as well as each human CYP1, has a unique DBC metabolite profile. 7H-dibenzo(c,g)carbazole 58-61 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 39-43