PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10978507-3	2000	Although the expression of P(AOD1) and P(DAS1) was completely repressed by the presence of glucose, formate-induced expression of P(FDH1) was not repressed by glucose.	formic acid	100-107	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	130-136	
19564482-2	2009	We used constraint-based metabolic modeling and computer-aided gene knockout simulations to identify five genes (ALT2, FDH1, FDH2, FUM1, and ZWF1), which, when deleted in combination, predicted formic acid secretion in Saccharomyces cerevisiae under aerobic growth conditions.	formic acid	194-205	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	119-123	
9226256-2	1997	In a batch culture experiment, although the fdh1 delta strain was still able to grow on methanol, its growth was greatly inhibited and a toxic level of formate was detected in the medium.	formic acid	152-159	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	44-48	
9226256-5	1997	Induction of FDH1 was not repressed in the presence of glucose when cells were grown on methylamine, choline, or formate, and expression of FDH1 was shown to be regulated at the mRNA level.	formic acid	113-120	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	13-17	
9226256-8	1997	As judged from these results, the main physiological role of FDH with all of the FDH1-inducing growth substrates seems to be detoxification of formate, and during growth on methanol, FDH seems to contribute significantly to the energy yield.	formic acid	143-150	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	81-85	
35328826-8	2022	When there was acetate without formate, FDH1 converted CO2 from glucose fermentation to formate and ATP and enhanced cell viability.	formic acid	88-95	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	40-44	
21246355-4	2011	To reinforce the capability for formic acid breakdown, the FDH1 gene was additionally overexpressed in the xylose-metabolizing recombinant yeast.	formic acid	32-43	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	59-63	
17156016-4	2006	To investigate whether incomplete formate consumption was by the unfavourable kinetics of yeast formate dehydrogenase (high k(M) for formate at low intracellular NAD(+) concentrations) strains were constructed in which the FDH1 and/or GPD2 genes, encoding formate dehydrogenase and glycerol-3-phosphate dehydrogenase, respectively, were overexpressed.	formic acid	34-41	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	223-227	
14534783-6	2003	Irrespective of whether induction was achieved with methanol or formate, the UAS-FM element enhanced the level of induction of the FDH1 promoter in a manner dependent on the number of copies, but independent of their orientation, and also converted the ACT1 promoter from a constitutive into an inducible element.	formic acid	64-71	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	131-135