PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16452484-1	2006	Pyruvate formate-lyase (PFL) catalyzes the non-oxidative conversion of pyruvate to formate and acetyl-CoA.	formic acid	9-16	uncharacterized protein	Chlamydomonas reinhardtii	24-27	
22687249-1	2012	Artificial microRNA technology was investigated as a means of down regulating metabolic pathways in the green alga Chlamydomonas reinhardtii, targeting pyruvate formate lyase (PFL1), which catalyzes the conversion of pyruvate to acetyl-CoA and formate during anoxic conditions.	formic acid	161-168	uncharacterized protein	Chlamydomonas reinhardtii	176-180	
22687249-4	2012	Under microaerobic conditions in the light, induced by sulphur-deprivation, knock-down of PFL1 resulted in reduced formate and ethanol production, increased net consumption of acetate and the excretion of lactate but no increase in the production of hydrogen.	formic acid	115-122	uncharacterized protein	Chlamydomonas reinhardtii	90-94	
22353371-5	2012	To further probe the system, we generated a double mutant (pfl1-1 adh1) that is unable to synthesize both formate and ethanol.	formic acid	106-113	uncharacterized protein	Chlamydomonas reinhardtii	59-63	
21293046-4	2011	Pfl catalyzes the nonoxidative generation of formate and acetyl-Coenzyme A (CoA) from pyruvate and CoA and is activated by Pfl activating enzyme (Pfla).	formic acid	45-52	uncharacterized protein	Chlamydomonas reinhardtii	0-3	
21293046-4	2011	Pfl catalyzes the nonoxidative generation of formate and acetyl-Coenzyme A (CoA) from pyruvate and CoA and is activated by Pfl activating enzyme (Pfla).	formic acid	45-52	uncharacterized protein	Chlamydomonas reinhardtii	123-126	
18245276-2	2008	It has two oxygen-sensitive [Fe-Fe] hydrogenases (EC 1.12.7.2) that are coupled to photosynthesis and, in addition, a formate- and ethanol-producing fermentative metabolism, which was proposed to be initiated by pyruvate formate-lyase (Pfl; EC 2.3.1.54).	formic acid	118-125	uncharacterized protein	Chlamydomonas reinhardtii	212-234	
18245276-6	2008	In this study, we proved the formate-producing activity of the putative Pfl1 enzyme by heterologous expression of the C. reinhardtii PFL1 cDNA in Escherichia coli and subsequent in vitro activity tests of the purified protein.	formic acid	29-36	uncharacterized protein	Chlamydomonas reinhardtii	72-76	
18245276-6	2008	In this study, we proved the formate-producing activity of the putative Pfl1 enzyme by heterologous expression of the C. reinhardtii PFL1 cDNA in Escherichia coli and subsequent in vitro activity tests of the purified protein.	formic acid	29-36	uncharacterized protein	Chlamydomonas reinhardtii	133-137