PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25571780-0 2015 Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta. gamma-Aminobutyric Acid 46-50 toll like receptor 4 Homo sapiens 14-34 25571780-8 2015 GABA synthesis at the presynaptic site is reduced upon activation of TLR4. gamma-Aminobutyric Acid 0-4 toll like receptor 4 Homo sapiens 69-73 21368176-3 2011 We report that a GABA(A) alpha2 siRNA vector (pHSVsiLA2) infused into the central nucleus of the amygdala (CeA) of alcohol-preferring (P) rats caused profound and selective reduction of binge drinking associated with inhibition of alpha2 expression, decreased GABA(A) receptor density, and inhibition of Toll-like receptor 4 (TLR4). gamma-Aminobutyric Acid 17-21 toll like receptor 4 Homo sapiens 304-324 21368176-3 2011 We report that a GABA(A) alpha2 siRNA vector (pHSVsiLA2) infused into the central nucleus of the amygdala (CeA) of alcohol-preferring (P) rats caused profound and selective reduction of binge drinking associated with inhibition of alpha2 expression, decreased GABA(A) receptor density, and inhibition of Toll-like receptor 4 (TLR4). gamma-Aminobutyric Acid 17-21 toll like receptor 4 Homo sapiens 326-330 21368176-7 2011 The data indicate that GABA(A) alpha2-regulated TLR4 expression in the CeA contributes to binge drinking and may be a key early neuroadaptation in excessive drinking. gamma-Aminobutyric Acid 23-27 toll like receptor 4 Homo sapiens 48-52