PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34817244-9	2021	Following exposure to TNF-alpha there was an increase in excitability of GABA neurons along with a reduction in glutamatergic synaptic transmission.	gamma-Aminobutyric Acid	73-77	tumor necrosis factor	Mus musculus	22-31	
18156782-5	2007	It was observed that GABA significantly inhibited the mRNA expression of iNOS, IL-1beta, and TNF-alpha, in LPS-stimulated RAW 264.7 cells.	gamma-Aminobutyric Acid	21-25	tumor necrosis factor	Mus musculus	93-102	
34817244-12	2021	Collectively, these data suggest that TNF-alpha differentially affects the function of GABA and DA neurons in female mice and enhances our understanding of how TNF-alpha mediated signaling modulates vlPAG function.	gamma-Aminobutyric Acid	87-91	tumor necrosis factor	Mus musculus	38-47	
34817244-12	2021	Collectively, these data suggest that TNF-alpha differentially affects the function of GABA and DA neurons in female mice and enhances our understanding of how TNF-alpha mediated signaling modulates vlPAG function.	gamma-Aminobutyric Acid	87-91	tumor necrosis factor	Mus musculus	160-169	
33361535-5	2021	GABA-salt attenuated diet-induced blood pressure increases, M1 polarization, and TNF-alpha and inducible nitric oxide synthase (NOS) levels in mouse aortas, and in salt treated macrophages in vitro.	gamma-Aminobutyric Acid	0-4	tumor necrosis factor	Mus musculus	81-90	
34036320-4	2021	The TNF-alpha secretion with DREM was elevated by exogenous addition of GABA and that with fDREM was in part mediated via A-type GABA receptors.	gamma-Aminobutyric Acid	72-76	tumor necrosis factor	Mus musculus	4-13	
34036320-4	2021	The TNF-alpha secretion with DREM was elevated by exogenous addition of GABA and that with fDREM was in part mediated via A-type GABA receptors.	gamma-Aminobutyric Acid	129-133	tumor necrosis factor	Mus musculus	4-13	
28808187-9	2016	In accordance with increased liver steatohepatitis, NASH-related and inflammatory gene expression (collagen alpha1, tissue inhibitor of metalloproteinase-1, TNF-alpha) in the liver was markedly increased in GABA-treated mice.	gamma-Aminobutyric Acid	207-211	tumor necrosis factor	Mus musculus	157-166	
30114280-8	2018	Furthermore, astrocytic TNFalpha levels were higher in GABA-Cnr1-/- mice, indicating that these morphological changes were accompanied by a more pro-inflammatory function.	gamma-Aminobutyric Acid	55-59	tumor necrosis factor	Mus musculus	24-32	
28808187-10	2016	Furthermore, GABA directly enhanced production of inflammatory cytokines including IL-6 and TNF-alpha in LPS activated RAW macrophage cells and increased TIB-73 hepatocyte death.	gamma-Aminobutyric Acid	13-17	tumor necrosis factor	Mus musculus	92-101	
27760889-9	2016	In accordance with increased liver steatohepatitis, NASH-related and inflammatory gene expression (collagen alpha1, tissue inhibitor of metalloproteinase-1, TNF-alpha) in the liver was markedly increased in GABA-treated mice.	gamma-Aminobutyric Acid	207-211	tumor necrosis factor	Mus musculus	157-166	
27760889-10	2016	Furthermore, GABA directly enhanced production of inflammatory cytokines including IL-6 and TNF-alpha in LPS activated RAW macrophage cells and increased TIB-73 hepatocyte death.	gamma-Aminobutyric Acid	13-17	tumor necrosis factor	Mus musculus	92-101	
23194644-3	2013	Daily GABA injections (200mg/kg) from day 3 onwards significantly augmented disease severity, which was associated with increased CNS mRNA expression levels of tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-6.	gamma-Aminobutyric Acid	6-10	tumor necrosis factor	Mus musculus	160-187	
23194644-3	2013	Daily GABA injections (200mg/kg) from day 3 onwards significantly augmented disease severity, which was associated with increased CNS mRNA expression levels of tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-6.	gamma-Aminobutyric Acid	6-10	tumor necrosis factor	Mus musculus	189-198