PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32446776-7 2020 Functional analyses results showed that the differential genes mainly related with posttranscriptional regulation of gene expression and protein localization to organelle and so on, which involved in AMPK, PI3K-Akt signaling pathway, and GABA-ergic synapse. gamma-Aminobutyric Acid 238-242 thymoma viral proto-oncogene 1 Mus musculus 211-214 30079374-8 2018 These results indicate that estradiol acts directly on GnRH neurons via the ERbeta/Akt/nNOS pathway at proestrus afternoon generating NO that retrogradely accelerates GABA and glutamate release from the presynaptic terminals contacting GnRH neurons. gamma-Aminobutyric Acid 167-171 thymoma viral proto-oncogene 1 Mus musculus 83-86 27615800-0 2016 Akting up in the GABA hypothesis of schizophrenia: Akt1 deficiency modulates GABAergic functions and hippocampus-dependent functions. gamma-Aminobutyric Acid 17-21 thymoma viral proto-oncogene 1 Mus musculus 51-55 21709230-5 2011 Unlike in adult brain or islet alpha-cells in which GABA exerts hyperpolarizing effects, in islet beta-cells, GABA produces membrane depolarization and Ca(2+) influx, leading to the activation of PI3-K/Akt-dependent growth and survival pathways. gamma-Aminobutyric Acid 110-114 thymoma viral proto-oncogene 1 Mus musculus 202-205 34296180-5 2021 In mice, we find that AKT1 is the most broadly expressed isoform, with expression in excitatory neurons and the sole detectable AKT isoform in gamma-aminobutyric acid ergic interneurons and microglia. gamma-Aminobutyric Acid 143-166 thymoma viral proto-oncogene 1 Mus musculus 128-131 22385968-2 2012 Here we show that regulation of dendritic development of newborn neurons by Disrupted-in-Schizophrenia 1 (DISC1) during adult hippocampal neurogenesis requires neurotransmitter GABA-induced, NKCC1-dependent depolarization through a convergence onto the AKT-mTOR pathway. gamma-Aminobutyric Acid 177-181 thymoma viral proto-oncogene 1 Mus musculus 253-256 35456004-4 2022 Studies have indicated the involvement of FMRP in a multitude of cellular pathways, and an absence of FMRP was shown to affect several neurotransmitter receptors, for example, the GABA receptor and intracellular signaling molecules such as Akt, ERK, mTOR, and GSK3. gamma-Aminobutyric Acid 180-184 thymoma viral proto-oncogene 1 Mus musculus 240-243