PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25284783-3 2014 Using a combination of molecular, imaging, and electrophysiological approaches, we delineate a GIT1/betaPIX/Rac1/PAK signaling pathway that modulates F-actin and is important for maintaining surface GABA(A)R levels, inhibitory synapse integrity, and synapse strength. gamma-Aminobutyric Acid 199-203 Rho guanine nucleotide exchange factor 7 Homo sapiens 100-107 25284783-3 2014 Using a combination of molecular, imaging, and electrophysiological approaches, we delineate a GIT1/betaPIX/Rac1/PAK signaling pathway that modulates F-actin and is important for maintaining surface GABA(A)R levels, inhibitory synapse integrity, and synapse strength. gamma-Aminobutyric Acid 199-203 Rho guanine nucleotide exchange factor 7 Homo sapiens 113-116 25284783-4 2014 We show that GIT1 and betaPIX are required for synaptic GABA(A)R surface stability through the activity of the GTPase Rac1 and downstream effector PAK. gamma-Aminobutyric Acid 56-60 Rho guanine nucleotide exchange factor 7 Homo sapiens 22-29 25284783-4 2014 We show that GIT1 and betaPIX are required for synaptic GABA(A)R surface stability through the activity of the GTPase Rac1 and downstream effector PAK. gamma-Aminobutyric Acid 56-60 Rho guanine nucleotide exchange factor 7 Homo sapiens 147-150 25284783-6 2014 Thus, the GIT1/betaPIX/Rac1/PAK pathway plays a crucial role in regulating GABA(A)R synaptic stability and hence inhibitory synaptic transmission with important implications for inhibitory plasticity and information processing in the brain. gamma-Aminobutyric Acid 75-79 Rho guanine nucleotide exchange factor 7 Homo sapiens 15-22 25284783-6 2014 Thus, the GIT1/betaPIX/Rac1/PAK pathway plays a crucial role in regulating GABA(A)R synaptic stability and hence inhibitory synaptic transmission with important implications for inhibitory plasticity and information processing in the brain. gamma-Aminobutyric Acid 75-79 Rho guanine nucleotide exchange factor 7 Homo sapiens 28-31